Anaphylactic shock reaction to dibutyl-phthalate-containing capsules

被引：5

作者：

Gall, H ^{[1
]}

Köhler, A ^{[1
]}

Peter, RU ^{[1
]}

机构：

[1] Univ Ulm, Dept Dermatol, D-89081 Ulm, Germany

来源：

DERMATOLOGY | 1999年 / 199卷 / 02期

关键词：

anaphylaxis; immediate-type allergy; drug auxiliary materials; dibutyl phthalate;

D O I：

10.1159/000018230

中图分类号：

R75 [皮肤病学与性病学];

学科分类号：

100206 ;

摘要：

We report on a patient who was taking a Gelomyrtol forte capsule, a mucosecretolytic herbal product, to treat an infection of the upper respiratory tract. Itching, urticaria and respiratory distress occurred after 20 min which culminated in anaphylactic shock. Prick tests were carried out with the individual substances from Gelomyrtol forte capsules. Dibutyl phthalate produced a strong positive result. It is used as a plasticizer in films covering tablets, dragees and capsules. As a triggering agent of anaphylactic reactions to drugs, the auxiliary materials, e.g. dibutyl phthalate, should also be taken into consideration.

引用

页码：169 / 170

页数：2

共 9 条

[1]

DEGROOT AC, 1994, SIDE EFFECTS DRUGS A

[2]

Fisher A. A., 1973, CONTACT DERMATITIS

[3]

Litt JZ, 1997, DRUG ERUPTION REFERE

[4]

Moneret-Vautrin DA, 1989, ALLERG IMMUNOL PARIS, V21, P198