Preventive and Therapeutic Effects of Punica granatum (Pomegranate) in Respiratory and Digestive Diseases: A Review

被引:9
作者
Alkhatib, Mariam [1 ]
Fayad, Chantal [1 ]
Badran, Adnan [2 ]
Hamade, Kamar [3 ]
Daou, Anis [4 ]
Baydoun, Elias [5 ]
Hijazi, Akram [1 ]
机构
[1] Platform Rech & Anal Sci Environm EDST PRASE, POB 14 6573, Hadath, Lebanon
[2] Univ Petra, Dept Nutr, Amman, Jordan
[3] Univ Picardie Jules Verne, Lab BIOPI, UMRT INRAE 1158 BioEcoAgro, F-80000 Amiens, France
[4] Qatar Univ, Coll Pharm, Pharmaceut Sci Dept, QU Hlth, POB 2713, Doha, Qatar
[5] Amer Univ Beirut, Dept Biol, Beirut PO, POB 11 0236, Beirut, Lebanon
来源
APPLIED SCIENCES-BASEL | 2022年 / 12卷 / 23期
关键词
pomegranate; cancer; antioxidant; respiratory; digestive; diseases; OBSTRUCTIVE PULMONARY-DISEASE; INDUCED GASTRIC DAMAGE; ELLAGIC ACID; PEEL EXTRACT; COLON-CANCER; ANTIBACTERIAL ACTIVITY; AQUEOUS EXTRACT; INFLUENZA-VIRUS; PLANT-EXTRACTS; L; POMEGRANATE;
D O I
10.3390/app122312326
中图分类号
O6 [化学];
学科分类号
0703 ;
摘要
The pomegranate fruit is made of white to deep purple seeds that are enclosed in a white, spongy, astringent membrane, also known as pericarp, covered by a thick red skin and a crown-shaped calyx. It contains a variety of beneficial ingredients, including flavonoids, ellagitannin, punicalagin, ellagic acid, vitamins, and minerals. Pomegranates possess numerous health benefits, and their use in disease treatment has been widely recognized since antiquity. This fruit was known to exhibit several biological properties, including antibacterial, anti-inflammatory, antioxidant, and anticancer activities. Pomegranate has been used in a variety of medical systems for the treatment and therapy of a wide range of diseases and illnesses. This review summarizes studies highlighting the potential role of pomegranate in the prevention and treatment of diseases related to respiratory and digestive systems.
引用
收藏
页数:19
相关论文
共 135 条
[1]   Chronic diseases 1 - The burden and costs of chronic diseases in low-income and middle-income countries [J].
Abegunde, Dele O. ;
Mathers, Colin D. ;
Adam, Taghreed ;
Ortegon, Monica ;
Strong, Kathleen .
LANCET, 2007, 370 (9603) :1929-1938
[2]   Pomegranate juice, total pomegranate ellagitannins, and punicalagin suppress inflammatory cell signaling in colon cancer cells [J].
Adams, LS ;
Seeram, NP ;
Aggarwal, BB ;
Takada, Y ;
Sand, D ;
Heber, D .
JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY, 2006, 54 (03) :980-985
[3]   Punica granatum suppresses colon cancer through downregulation of Wnt/β-Catenin in rat model [J].
Ahmed, Hanaa H. ;
El-Abhar, Hanan S. ;
Hassanin, Elsayed Abdul Khalik ;
Abdelkader, Noha F. ;
Shalaby, Mohamed B. .
REVISTA BRASILEIRA DE FARMACOGNOSIA-BRAZILIAN JOURNAL OF PHARMACOGNOSY, 2017, 27 (05) :627-635
[4]   The inhibition of gastric mucosal injury by Punica granatum L. (pomegranate) methanolic extract [J].
Ajaikumar, KB ;
Asheef, M ;
Babu, BH ;
Padikkala, J .
JOURNAL OF ETHNOPHARMACOLOGY, 2005, 96 (1-2) :171-176
[5]   Protective effects of Punica granatum in experimentally-induced gastric ulcers [J].
Alam, Mohd Sarfaraz ;
Alam, Mohd Aftab ;
Ahmad, Sayeed ;
Najmi, Abul Kalam ;
Asif, Mohd ;
Jahangir, Tamanna .
TOXICOLOGY MECHANISMS AND METHODS, 2010, 20 (09) :572-578
[6]  
Alkhatib AJ, 2021, PSM. Biological. Res., V6, P1
[7]  
American Cancer Society, 2020, Global Cancer Facts Figures | American Cancer Society
[8]   Anti-proliferative activity and protection against oxidative DNA damage by punicalagin isolated from pomegranate husk [J].
Aqil, Farrukh ;
Munagala, Radha ;
Vadhanam, Manicka V. ;
Kausar, Nina ;
Jeyabalan, Jeyaprakash ;
Schultz, David J. ;
Gupta, Ramesh C. .
FOOD RESEARCH INTERNATIONAL, 2012, 49 (01) :345-353
[9]   Targeting the canonical Wnt/-catenin pathway in hematological malignancies [J].
Ashihara, Eishi ;
Takada, Tetsuya ;
Maekawa, Taira .
CANCER SCIENCE, 2015, 106 (06) :665-671
[10]   Discovery and resupply of pharmacologically active plant-derived natural products: A review [J].
Atanasov, Atanas G. ;
Waltenberger, Birgit ;
Pferschy-Wenzig, Eva-Maria ;
Linder, Thomas ;
Wawrosch, Christoph ;
Uhrin, Pavel ;
Temml, Veronika ;
Wang, Limei ;
Schwaiger, Stefan ;
Heiss, Elke H. ;
Rollinger, Judith M. ;
Schuster, Daniela ;
Breuss, Johannes M. ;
Bochkov, Valery ;
Mihovilovic, Marko D. ;
Kopp, Brigitte ;
Bauer, Rudolf ;
Dirsch, Verena M. ;
Stuppner, Hermann .
BIOTECHNOLOGY ADVANCES, 2015, 33 (08) :1582-1614