Efficient synthesis of 2H-chromene derivatives via a dual-organocatalytic reaction

被引：6

作者：

Somprasong, Siriphong ^{[1
,2
]}

Prasitwatcharakorn, Watcharapon ^{[1
,2
]}

Luanphaisarnnont, Torsak ^{[1
,2
]}

机构：

[1] Mahidol Univ, Fac Sci, Dept Chem, Bangkok 10400, Thailand

[2] Mahidol Univ, Fac Sci, Ctr Excellence Innovat Chem, Bangkok 10400, Thailand

来源：

TETRAHEDRON LETTERS | 2020年 / 61卷 / 42期

关键词：

2H-Chromenes; Catalysis; p-Toluenesulfonic acid; Pyrrolidine; Regioselective synthesis; FUNCTIONALIZED; 2H-CHROMENES; 4+2 CYCLOADDITION; SALICYLALDEHYDES; CYCLOCONDENSATION; 2H-1-BENZOPYRANS; NANOPARTICLES; CHROMENES; ALDEHYDES; CATALYST;

D O I：

10.1016/j.tetlet.2020.152402

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

An efficient synthetic method was developed for the selective construction of 2H-chromene derivatives from various salicylaldehydes and acetylenic diesters using a dual catalyst system (p-toluenesulfonic acid monohydrate and pyrrolidine). The advantages of this transformation include high selectivity, good functional group tolerance, operational simplicity, and mild reaction conditions. (C) 2020 Elsevier Ltd. All rights reserved.

引用

页数：4