Synthesis, structure and transformations of 2-iminoimidazolidines into novel fused heterocyclic ring systems

被引：3

作者：

Kornicka, A

Saczewski, F

Gdaniec, M

机构：

[1] Med Univ Gdansk, Dept Chem Technol Drugs, PL-80416 Gdansk, Poland

[2] Adam Mickiewicz Univ Poznan, Fac Chem, PL-60780 Poznan, Poland

来源：

HETEROCYCLES | 2006年 / 68卷 / 04期

关键词：

imidazolidine; imidazo[2 ',1 ': 4,5][1,3,5]thiadiazino[2,3-b]quinazoline-5-thione; 4H-3,1-benzoxazine; X-ray analysis;

D O I：

10.3987/COM-06-10666

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Reaction of 2-chloro-4,5-dihydroimidazole (1) with 2-aminobenzylamines (2a-d) afforded 2-[(imidazolidin-2-ylideneamino)methyl]anilines (3a-d) which upon treatment with carbon disulfide gave 2,3-dihydro-12H-imidazo[2',1':4,5][1,3,5]thiadiazino[2,3-b]quinazolin-5-thiones (4a-d) and 3,4-dihydro-1H-quinazolin-2-thiones (5a-c). Analogous reaction of 1 with 2-aminobenzyl alcohol (6) led to the formation of [2-(4,5-dihydrol 1H-imidazol-2-ylamino)phenyl]methanol hydrochloride (7) which was transformed into 1-(4H-3,1-benzoxazin-2-yl)imidazolidin-2-thione (8).

引用

页码：687 / 699

页数：13

共 15 条

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