In this paper, elasto-plastic XFEM simulations have been performed to evaluate the fatigue life of plane crack problems in the presence of various defects. The stress-strain response of the material is modeled by Ramberg-Osgood equation. The von-Mises failure criterion has been used with isotropic hardening. The J-integral for two fracture modes (mode-I and mode-II) is obtained by decomposing the displacement and stress fields into their symmetric and antisymmetric parts, then individual stress intensity factors are extracted from J-integral. The fatigue life obtained by EPFM is found quite close to that obtained by LEFM.