Safety and factors related to survival after percutaneous endoscopic gastrostomy in ALS

被引：100

作者：

Chiò, A ^{[1
]}

Finocchiaro, E

Meineri, P

Bottacchi, E

Schiffer, D

机构：

[1] Univ Turin, Dept Neurosci, I-10126 Turin, Italy

[2] San Giovanni Hosp, Dept Clin Nutr, Turin, Italy

[3] Gen Reg Hosp, Dept Neurol, Aosta, Italy

[4] Univ Turin, Dept Gastroenterol, I-10126 Turin, Italy

[5] Santa Croce Hosp, Dept Neurol, Cuneo, Italy

来源：

NEUROLOGY | 1999年 / 53卷 / 05期

关键词：

percutaneous endoscopic gastrostomy; amyotrophic lateral sclerosis;

D O I：

10.1212/WNL.53.5.1123

中图分类号：

R74 [神经病学与精神病学];

学科分类号：

摘要：

Percutaneous endoscopic gastrostomy (PEG) has been proposed as symptomatic treatment of dysphagia in patients with ALS. Safety and factors related to survival after PEG were analyzed in 50 consecutive ALS patients. No major acute or long-term complications were observed. Stabilization or increase in weight were observed after PEG. Median survival after PEG was 185 days, with a worse outcome in patients with weight loss greater than or equal to 10% healthy body weight and forced vital capacity <65%. PEG may be a useful option in the symptomatic treatment of dysphagia in ALS.

引用

页码：1123 / 1125

页数：3

共 9 条

[1] ARORA NS, 1981, AM REV RESPIR DIS, V126, P5
[2] BAAS NH, 1990, J NEUROL REHABIL, V4, P227
[3] Gelinas Deborah F., 1997, Neurology, V48, pS9
[4] Management of ALS: Nutritional care
Kasarskis, EJ
Neville, HE
[J]. NEUROLOGY, 1996, 47 (04) : S118 - S120
[5] PERCUTANEOUS ENDOSCOPIC GASTROSTOMY IN PATIENTS WITH AMYOTROPHIC-LATERAL-SCLEROSIS AND IMPAIRED PULMONARY-FUNCTION
MATHUSVLIEGEN, LMH
LOUWERSE, LS
MERKUS, MP
TYTGAT, GNJ
DEJONG, JMBV
[J]. GASTROINTESTINAL ENDOSCOPY, 1994, 40 (04) : 463 - 469
[6] PERCUTANEOUS ENDOSCOPIC GASTROSTOMY AND ENTERAL NUTRITION IN AMYOTROPHIC-LATERAL-SCLEROSIS
MAZZINI, L
CORRA, T
ZACCALA, M
MORA, G
DELPIANO, M
GALANTE, M
[J]. JOURNAL OF NEUROLOGY, 1995, 242 (10) : 695 - 698
[7] MITSUMOTO H, 1998, AMYOTROPHIC LATERAL, P421
[8] Parmar M.K. B., 1995, SURVIVAL ANAL PRACTI
[9] SALACHAS F, 1996, 7 INT S ALSMND

← 1 →