Remote ischaemic preconditioning: is it a flag on the field?

被引:6
作者
Moscarelli, M. [1 ]
Angelini, G. D. [1 ,2 ]
Suleiman, S. [2 ]
Fiorentino, F. [1 ]
Punjabi, P. P. [1 ]
机构
[1] Univ London Imperial Coll Sci Technol & Med, Hammersmith Hosp, NHLI, London W12 0HS, England
[2] Univ Bristol, Bristol Heart Inst, Bristol, Avon, England
来源
PERFUSION-UK | 2015年 / 30卷 / 06期
关键词
ischaemia; reperfusion injury; preconditioning (cardiac); RANDOMIZED CONTROLLED-TRIAL; ARTERY-BYPASS SURGERY; PERCUTANEOUS CORONARY INTERVENTION; MYOCARDIAL INFARCT SIZE; CARDIAC-SURGERY; CARDIOVASCULAR-SURGERY; VALVE-REPLACEMENT; GRAFT-SURGERY; METAANALYSIS; INJURY;
D O I
10.1177/0267659115570720
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
Ischaemic preconditioning is one of several different techniques that have been proposed to render the heart more resistant to ischaemia/reperfusion injuries. A significant reduction of troponin release is proof of concept', however, whether ischaemic preconditioning leads to improved clinical outcomes is still to be proven. Moreover, the exact mechanism of action still remains unknown since very few studies have investigated the signal transmission in humans.
引用
收藏
页码:438 / 447
页数:10
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