Evidence for Human Adaptation and Foodborne Transmission of Livestock-Associated Methicillin-Resistant Staphylococcus aureus

被引：85

作者：

Larsen, Jesper ^{[1
]}

Stegger, Marc ^{[1
,5
]}

Andersen, Paal S. ^{[1
,2
]}

Petersen, Andreas ^{[1
]}

Larsen, Anders R. ^{[1
]}

Westh, Henrik ^{[2
,3
]}

Agerso, Yvonne ^{[4
]}

Fetsch, Alexandra ^{[7
]}

Kraushaar, Britta ^{[7
]}

Kaesbohrer, Annemarie ^{[7
]}

Fessler, Andrea T. ^{[8
]}

Schwarz, Stefan ^{[8
]}

Cuny, Christiane ^{[9
]}

Witte, Wolfgang ^{[9
]}

Butaye, Patrick ^{[10
,12
]}

Denis, Olivier ^{[11
]}

Haenni, Marisa ^{[13
]}

Madec, Jean-Yves ^{[13
]}

Jouy, Eric ^{[16
]}

Laurent, Frederic ^{[14
,15
]}

Battisti, Antonio ^{[17
]}

Franco, Alessia ^{[17
]}

Alba, Patricia ^{[17
]}

Mammina, Caterina ^{[19
]}

Pantosti, Annalisa ^{[18
]}

Monaco, Monica ^{[18
]}

Wagenaar, Jaap A. ^{[20
,22
]}

de Boer, Enne ^{[21
]}

van Duijkeren, Engeline ^{[23
]}

Heck, Max ^{[23
]}

Dominguez, Lucas ^{[24
]}

Torres, Carmen ^{[25
]}

Zarazaga, Myriam ^{[25
]}

Price, Lance B. ^{[5
,6
]}

Skov, Robert L. ^{[1
]}

机构：

[1] Statens Serum Inst, Copenhagen, Denmark

[2] Univ Copenhagen, Frederiksberg, Denmark

[3] Hvidovre Univ Hosp, Lyngby, Denmark

[4] Tech Univ Denmark, Lyngby, Denmark

[5] Translat Genom Res Inst, Flagstaff, AZ USA

[6] George Washington Univ, Washington, DC USA

[7] Fed Inst Risk Assessment, Berlin, Germany

[8] Friedrich Loeffler Inst, Neustadt, Germany

[9] Robert Koch Inst, Wernigerode, Germany

[10] Univ Ghent, Brussels, Belgium

[11] Univ Libre Bruxelles, Brussels, Belgium

[12] Ross Univ, Sch Vet Med, Basseterre, St Kitts & Nevi

[13] French Agcy Food Environm & Occupat Hlth & Safety, Lyon, France

[14] Univ Claude Bernard Lyon 1, Ploufragan, France

[15] Hosp Civils Lyon, Ploufragan, France

[16] French Agcy Food Environm & Occupat Hlth & Safety, Ploufragan, France

[17] Ist Zooprofilatt Sperimentale Reg Lazio & Toscana, Rome, Italy

[18] Ist Super Sanita, Rome, Italy

[19] Univ Palermo, I-90133 Palermo, Italy

[20] Univ Utrecht, Utrecht, Netherlands

[21] Netherlands Food & Consumer Prod Safety Author, Utrecht, Netherlands

[22] Cent Vet Inst, Lelystad, Netherlands

[23] Natl Inst Publ Hlth & Environm, Bilthoven, Netherlands

[24] Univ Complutense Madrid, Logrono, Spain

[25] Univ La Rioja, Logrono, Spain

来源：

CLINICAL INFECTIOUS DISEASES | 2016年 / 63卷 / 10期

基金：

美国国家卫生研究院;

关键词：

MRSA; host adaptation; foodborne transmission; poultry; livestock;

D O I：

10.1093/cid/ciw532

中图分类号：

R392 [医学免疫学]; Q939.91 [免疫学];

学科分类号：

100102 ;

摘要：

We investigated the evolution and epidemiology of a novel live-stock-associated methicillin-resistant Staphylococcus aureus strain, which colonizes and infects urban-dwelling Danes even without a Danish animal reservoir. Genetic evidence suggests both poultry and human adaptation, with poultry meat implicated as a probable source.

引用

页码：1349 / 1352

页数：4

共 12 条

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