Nuclear imaging and target volumes for radiotherapy

被引:1
作者
Dubray, B. [1 ]
Thureau, S. [1 ,2 ]
Nkhali, L. [1 ]
Modzelewski, R. [2 ]
Doyeux, K. [1 ]
Vera, P. [2 ]
机构
[1] Univ Rouen, QuantIF LITIS, Ctr Henri Becquerel,UFR Med & Pharm, Dept Radiotherapie & Phys Med,EA Equipe Accueil 4, F-76000 Rouen, France
[2] Univ Rouen, QuantIF LITIS, Ctr Henri Becquerel,UFR Med & Pharm, Dept Med Nucl,EA Equipe Accueil 4108, F-76000 Rouen, France
来源
MEDECINE NUCLEAIRE-IMAGERIE FONCTIONNELLE ET METABOLIQUE | 2013年 / 37卷 / 05期
关键词
PET/CT; FDG; F-miso; FLT; Radiotherapy; Lung cancer; CELL LUNG-CANCER; POSITRON-EMISSION-TOMOGRAPHY; MODULATED RADIATION-THERAPY; DOSE PRESCRIPTION; STAGE MIGRATION; TUMOR VOLUME; CT; SURVIVAL; PET; REDUCTION;
D O I
10.1016/j.mednuc.2013.03.169
中图分类号
R36 [病理学];
学科分类号
100104 ;
摘要
Nuclear imaging plays a key role in the management of malignant tumours by radiation oncologists. Focusing on lung cancers, this review emphasizes how FDG PET/CT is determinant for initial staging and indication of curative-intent radiotherapy. The treatment machines are nowadays able to achieve precise dose distributions, taking into account the functional characteristics of malignant tumours and their evolution during radiotherapy. Major technical difficulties still have to be overcome, not the least being the inescapable necessity to register all images on a planning CT scan. The clinical validation of these innovative approaches and their diffusion in daily routine require a very close collaboration between both specialties, based on a common language and understanding of radiotherapy target volumes. (C) 2013 Elsevier Masson SAS. All rights reserved.
引用
收藏
页码:198 / 202
页数:5
相关论文
共 56 条
[41]   Reduction of observer variation using matched CT-PET for lung cancer delineation: A three-dimensional analysis [J].
Steenbakkers, RJHM ;
Duppen, JC ;
Fitton, I ;
Deurloo, KEI ;
Zijp, LJ ;
Comans, EFI ;
Uitterhoeve, ALJ ;
Rodrigus, PTR ;
Kramer, GWP ;
Bussink, J ;
De Jaeger, K ;
Belderbos, JSA ;
Nowak, PJCM ;
van Herk, M ;
Rasch, CRN .
INTERNATIONAL JOURNAL OF RADIATION ONCOLOGY BIOLOGY PHYSICS, 2006, 64 (02) :435-448
[42]  
Ung Y, 2011, ASCO M ABSTRACTS S, V29, P7018
[43]   PET-CT-based auto-contouring in non-small-cell lung cancer correlates with pathology and reduces interobserver variability in the delineation of the primary tumor and involved nodal volumes [J].
Van Baardwijk, Angela ;
Bosmans, Geert ;
Boersma, Liesbeth ;
Buijsen, Jeroen ;
Wanders, Stofferinus ;
Hochstenbag, Monique ;
Van Suylen, Robert-Jan ;
Dekker, Andre ;
Dehing-Oberije, Cary ;
Houben, Ruud ;
Bentzen, Soren M. ;
Van Kroonenburgh, Marinus ;
Lambin, Philippe ;
De Ruysscher, Dirk .
INTERNATIONAL JOURNAL OF RADIATION ONCOLOGY BIOLOGY PHYSICS, 2007, 68 (03) :771-778
[44]   Mature Results of an Individualized Radiation Dose Prescription Study Based on Normal Tissue Constraints in Stages I to III Non-Small-Cell Lung Cancer [J].
van Baardwijk, Angela ;
Wanders, Stofferinus ;
Boersma, Liesbeth ;
Borger, Jacques ;
Oellers, Michel ;
Dingemans, Anne-Marie C. ;
Bootsma, Gerben ;
Geraedts, Wiel ;
Pitz, Cordula ;
Lunde, Ragnar ;
Lambin, Philippe ;
De Ruysscher, Dirk .
JOURNAL OF CLINICAL ONCOLOGY, 2010, 28 (08) :1380-1386
[45]   MICROSCOPIC DISEASE EXTENSION IN THREE DIMENSIONS FOR NON-SMALL-CELL LUNG CANCER: DEVELOPMENT OF A PREDICTION MODEL USING PATHOLOGY-VALIDATED POSITRON EMISSION TOMOGRAPHY AND COMPUTED TOMOGRAPHY FEATURES [J].
van Loon, Judith ;
Siedschlag, Christian ;
Stroom, Joep ;
Blauwgeers, Hans ;
van Suylen, Robert-Jan ;
Knegjens, Joost ;
Rossi, Maddalena ;
van Baardwijk, Angela ;
Boersma, Liesbeth ;
Klomp, Houke ;
Vogel, Wouter ;
Burgers, Sjaak ;
Gilhuijs, Kenneth .
INTERNATIONAL JOURNAL OF RADIATION ONCOLOGY BIOLOGY PHYSICS, 2012, 82 (01) :448-456
[46]   Effectiveness of positron emission tomography in the preoperative assessment of patients with suspected non-small-cell lung cancer: the PLUS multicentre randomised trial [J].
van Tinteren, H ;
Hoekstra, OS ;
Smit, EF ;
van den Bergh, JHAM ;
Schreurs, AJM ;
Stallaert, RALM ;
van Velthoven, PCM ;
Comans, EFI ;
Diepenhorst, FW ;
Verboom, P ;
van Mourik, JC ;
Postmus, PE ;
Boers, M ;
Teule, GJJ .
LANCET, 2002, 359 (9315) :1388-1392
[47]   Early stage non-small-cell lung cancer: challenges in staging and adjuvant treatment: evidence-based staging [J].
Vansteenkiste, J. ;
Dooms, C. ;
De Leyn, P. .
ANNALS OF ONCOLOGY, 2010, 21 :189-195
[48]   Simultaneous positron emission tomography (PET) assessment of metabolism with 18F-fluoro-2-deoxy-D-glucose (FDG), proliferation with 18F-fluoro-thymidine (FLT), and hypoxia with 18fluoro-misonidazole (F-miso) before and during radiotherapy in patients with non-small-cell lung cancer (NSCLC): A pilot study [J].
Vera, Pierre ;
Bohn, Pierre ;
Edet-Sanson, Agathe ;
Salles, Alice ;
Hapdey, Sebastien ;
Gardin, Isabelle ;
Menard, Jean-Francois ;
Modzelewski, Romain ;
Thiberville, Luc ;
Dubray, Bernard .
RADIOTHERAPY AND ONCOLOGY, 2011, 98 (01) :109-116
[49]   Gradient-based delineation of the primary GTV on FDG-PET in non-small cell lung cancer: A comparison with threshold-based approaches, CT and surgical specimens [J].
Wanet, Marie ;
Lee, John Aldo ;
Weynand, Birgit ;
De Bast, Marc ;
Poncelet, Alain ;
Lacroix, Valerie ;
Coche, Emmanuel ;
Gregoire, Vincent ;
Geets, Xavier .
RADIOTHERAPY AND ONCOLOGY, 2011, 98 (01) :117-125
[50]   Adaptive radiotherapy planning on decreasing gross tumor volumes as seen on megavoltage computed tomography images [J].
Woodford, Curtis ;
Yartsev, Slav ;
Dar, A. Rashid ;
Bauman, Glenn ;
Van Dyk, Jake .
INTERNATIONAL JOURNAL OF RADIATION ONCOLOGY BIOLOGY PHYSICS, 2007, 69 (04) :1316-1322