Spontaneous Coronary Artery Dissection JACC State-of-the-Art Review

被引:321
作者
Hayes, Sharonne N. [1 ]
Tweet, Marysia S. [1 ]
Adlam, David [2 ,3 ]
Kim, Esther S. H. [4 ]
Gulati, Rajiv [1 ]
Price, Joel E. [5 ]
Rose, Carl H. [6 ]
机构
[1] Mayo Clin, Dept Cardiovasc Med, Rochester, MN USA
[2] Univ Leicester, Dept Cardiovasc Med, Leicester, Leics, England
[3] Univ Leicester, NIHR Leicester Biomed Res Ctr, Leicester, Leics, England
[4] Vanderbilt Univ, Med Ctr, Div Cardiol, Nashville, TN USA
[5] Univ British Columbia, Div Cardiac Surg, Vancouver, BC, Canada
[6] Mayo Clin, Div Maternal & Fetal Med, Rochester, MN USA
关键词
fibromuscular dysplasia; genetics; myocardial infarction; pregnancy-associated; SCAD; women; ACUTE MYOCARDIAL-INFARCTION; FIBROMUSCULAR DYSPLASIA; FOLLOW-UP; CARDIOVASCULAR-DISEASE; INTRACRANIAL ANEURYSM; CLINICAL PRESENTATION; PREGNANCY; ASSOCIATION; PREVALENCE; MANAGEMENT;
D O I
10.1016/j.jacc.2020.05.084
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
Over the past decade, spontaneous coronary artery dissection (SCAD) has emerged as an important cause of myocardial infarction, particularly among younger women. The pace of knowledge acquisition has been rapid, but ongoing challenges include accurately diagnosing SCAD and improving outcomes. Many SCAD patients experience substantial post-SCAD symptoms, recurrent SCAD, and psychosocial distress. Considerable uncertainty remains about optimal management of associated conditions, risk stratification and prevention of complications, recommendations for physical activity, reproductive planning, and the role of genetic evaluations. This review provides a clinical update on the diagnosis and management of patients with SCAD, including pregnancy-associated SCAD and pregnancy after SCAD, and highlight high-priority knowledge gaps that must be addressed. (C) 2020 the American College of Cardiology Foundation. Published by Elsevier. All rights reserved.
引用
收藏
页码:961 / 984
页数:24
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