One-step syntheses of alkyl glycosides and alkyl-substituted DNA oligomers by chemoselective glycosidations using DNA bases

被引:0
|
作者
Nishikubo, Y [1 ]
Sasaki, K [1 ]
Matsumura, S [1 ]
Toshima, K [1 ]
机构
[1] Keio Univ, Dept Appl Chem, Fac Sci & Technol, Kohoku Ku, Yokohama, Kanagawa 2238522, Japan
关键词
carbohydrate; DNA; RNA; glycosidation; alkyl glycoside; modified DNA oligomer;
D O I
10.1016/j.tetlet.2005.12.049
中图分类号
O62 [有机化学];
学科分类号
070303 ; 081704 ;
摘要
The simple and practical synthesis of alkyl glycosides by novel chemoselective glycosidations using natural resources, DNA and RNA nucleosides, was realized, and the one-step synthesis of chemoselectively modified DNA oligomers using the glycosidation method was also demonstrated. (c) 2005 Elsevier Ltd. All rights reserved.
引用
收藏
页码:1041 / 1045
页数:5
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