Primary cutaneous B-cell lymphoma in a child

被引:13
作者
Condarco, Tania [1 ]
Sagatys, Elizabeth [2 ]
Prakash, Amy V. [2 ]
Rezania, Dorna [2 ]
Cualing, Hernani [2 ]
机构
[1] Univ S Florida, Coll Med, Tampa, FL USA
[2] Univ S Florida, Dept Pathol & Lab Med, Tampa, FL USA
关键词
pediatric; cutaneous lymphoma; B-cell; follicle center;
D O I
10.1080/15513810802319442
中图分类号
R36 [病理学];
学科分类号
100104 ;
摘要
Primary cutaneous B-cell lymphoma is a B-cell lymphoma of the skin with no evidence of extracutaneous involvement at the time of diagnosis. In this report, we describe an 8-year-old boy who presented with a firm, alopecic, skin-colored, smooth nodule over the right frontal scalp. Histological examination revealed a mid-to deep-dermal mononuclear lesion. Immunohistochemical staining revealed a B-cell population that was CD10(+), CD5(-), CD21(+), and bcl2(-). This pattern of reactivity is characteristic of primary cutaneous B-cell lymphoma of follicle-center subtype. To the best of our knowledge, this is the first report of this type of cutaneous lymphoma in a child.
引用
收藏
页码:206 / 214
页数:9
相关论文
共 25 条
[1]  
BURG G, 1998, CURR PROBL DERMATOL, P137
[2]   Cutaneous lymphoma - Understanding the new classification schemes [J].
Duncan, LM .
DERMATOLOGIC CLINICS, 1999, 17 (03) :569-+
[3]   The molecular biology of pediatric lymphomas [J].
Goldsby, RE ;
Carroll, WL .
JOURNAL OF PEDIATRIC HEMATOLOGY ONCOLOGY, 1998, 20 (04) :282-296
[4]   Bcl-2 protein expression is the strongest independent prognostic factor of survival in primary cutaneous large B-cell lymphomas [J].
Grange, F ;
Petrella, T ;
Beylot-Barry, M ;
Joly, P ;
D'Incan, M ;
Delaunay, M ;
Machet, L ;
Avril, MF ;
Dalac, S ;
Bernard, P ;
Carlotti, A ;
Esteve, E ;
Vergier, B ;
Dechelotte, P ;
Cassagnau, E ;
Courville, P ;
Saiag, P ;
Laroche, L ;
Bagot, M ;
Wechsler, J .
BLOOD, 2004, 103 (10) :3662-3668
[5]   B-CELL LINEAGE CONFERS A FAVORABLE OUTCOME AMONG CHILDREN AND ADOLESCENTS WITH LARGE-CELL LYMPHOMA - A PEDIATRIC-ONCOLOGY-GROUP STUDY [J].
HUTCHISON, RE ;
BERARD, CW ;
SHUSTER, JJ ;
LINK, MP ;
PICK, TE ;
MURPHY, SB .
JOURNAL OF CLINICAL ONCOLOGY, 1995, 13 (08) :2023-2032
[6]   PRIMARY NON-HODGKINS-LYMPHOMA OF THE SKIN IN CHILDREN [J].
KAWASAKI, H ;
ITO, K ;
MATSUSHITA, T ;
TAKAYAMA, J ;
OHIRA, M .
ACTA PAEDIATRICA, 1994, 83 (12) :1315-1316
[7]   Primary B-cell lymphomas of the skin [J].
Kerl, H ;
Cerroni, L .
ANNALS OF ONCOLOGY, 1997, 8 :29-32
[8]  
LEBOIT PE, 2006, PATHOL GENET SKIN TU
[9]  
LONG JC, 1976, CANCER, V38, P1282, DOI 10.1002/1097-0142(197609)38:3<1282::AID-CNCR2820380331>3.0.CO
[10]  
2-N