False negative rate of fine-needle aspiration in thyroid nodules: impact of nodule size and ultrasound pattern

被引:13
作者
Ahn, Hye Shin [1 ]
Na, Dong Gyu [2 ]
Baek, Jung Hwan [3 ,4 ]
Sung, Jin Yong [5 ]
Kim, Ji-Hoon [6 ]
机构
[1] Chung Ang Univ, Coll Med, Chung Ang Univ Hosp, Dept Radiol, Seoul, South Korea
[2] GangNeung Asan Hosp, Dept Radiol, 38 Bangdong Gil, Kangnung 25440, South Korea
[3] Univ Ulsan, Coll Med, Asan Med Ctr, Dept Radiol, Seoul, South Korea
[4] Univ Ulsan, Coll Med, Asan Med Ctr, Res Inst Radiol, Seoul, South Korea
[5] Daerim St Marys Hosp, Thyroid Ctr, Dept Radiol, Seoul, South Korea
[6] Seoul Natl Univ, Coll Med, Seoul Natl Univ Hosp, Dept Radiol, Seoul, South Korea
来源
HEAD AND NECK-JOURNAL FOR THE SCIENCES AND SPECIALTIES OF THE HEAD AND NECK | 2019年 / 41卷 / 04期
关键词
false negative rate; fine needle aspiration; thyroid cancer; thyroid nodule; ultrasound; FOLLICULAR VARIANT; BETHESDA SYSTEM; ASSOCIATION GUIDELINES; SONOGRAPHIC FEATURES; CONSENSUS STATEMENT; CM; CYTOLOGY; MANAGEMENT; CANCER; ULTRASONOGRAPHY;
D O I
10.1002/hed.25530
中图分类号
R76 [耳鼻咽喉科学];
学科分类号
100213 ;
摘要
Background To retrospectively evaluate the false negative rate of ultrasound-guided fine needle aspiration (FNA) according to the nodule size and ultrasound pattern. Methods We included 432 consecutive thyroid nodules from 384 patients who underwent ultrasound-guided FNA with benign results (>= 1 cm). The false negative rate in the nodules was assessed according to the nodule size and ultrasound pattern based on the Korean-Thyroid Imaging Reporting and Data System (K-TIRADS). Results The overall false negative rate was 3.2%. There was a trend toward an increasing false negative rate as the K-TIRADS score increased (P < .001). In low or high suspicion nodules (K-TIRADS 3 and 5), there was no significant difference in false negative rate according to the nodule size; however, among the intermediate suspicion nodules (K-TIRADS 4), the false negative rate was higher in large nodules (>= 3 cm, P = .039). Conclusion The impact of nodule size on the false negative rate differed according to the ultrasound pattern.
引用
收藏
页码:967 / 973
页数:7
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