Bioprospecting Endophytic Fungi Inhabiting Indian Medicinal Plants

被引:0
|
作者
Chowdhary, Kanika [1 ]
Kaushik, Nutan [1 ]
机构
[1] TERI Inst, Lodhi Estate, Delhi 110003, India
来源
关键词
Endophytic fungi; Medicinal plants; Antimycotic activity; Secondary metabolites;
D O I
10.1007/s40009-020-00934-y
中图分类号
O [数理科学和化学]; P [天文学、地球科学]; Q [生物科学]; N [自然科学总论];
学科分类号
07 ; 0710 ; 09 ;
摘要
The present study investigates antimycotic potential of endophytic fungi towards economically relevant plant pathogenic organisms, viz.Rhizoctonia solani, Fusarium oxysporum, Sclerotinia sclerotiorumandBotrytis cinerea. Plant-derived by-products such as saponins and essential oils are considered as effective antifungal agents. Therefore, essential-oil-producing plants, viz.Ocimum sanctumandMentha piperita, and saponin-producing plants, viz.Asparagus racemosusandChlorophytum borivilianum, were selected as host plants. Bioactive secondary metabolites identified by GC-MS analysis, i.e. 6-pentyl-5,6-dihydro-2H-pyran-2-one and methyl hexadecanoic acid, demonstrated strong antimycotic activity towardsF.oxysporumand S.sclerotiorumhaving IC(50)value of 0.662 ppm and 1.002 ppm, respectively. Sulphamethazine was recognised as potent antifungal metabolite in bioactive fraction ofAcremoniumsp. through UPLC-MS/MS dereplication.
引用
收藏
页码:173 / 176
页数:4
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