Focus on molecules: Optineurin

被引：14
作者：
Chalasani, Madhavi Latha [1 ]
Balasubranianian, Dorairajan [1 ]
Swarup, Ghanshyam [2 ]
机构：
[1] LV Prasad Eye Inst, Hyderabad 500034, Andhra Pradesh, India
[2] Ctr Cellular & Mol Biol, Hyderabad 500007, Andhra Pradesh, India
来源：
EXPERIMENTAL EYE RESEARCH | 2008年 / 87卷 / 01期
关键词：
optineurin; glaucoma; retinal ganglion cells; mutation; cell death; tumor necrosis factor; NF-kappa B;
D O I：
10.1016/j.exer.2007.10.021
中图分类号：
R77 [眼科学];
学科分类号：
100212 ;
摘要：
引用
收藏
页码：1 / 2
页数：2
相关论文
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  • [1] A glaucoma-associated mutant of optineurin selectively induces death of retinal ganglion cells which is inhibited by antioxidants
    Chalasani, Madhavi Latha
    Radha, Vegesna
    Gupta, Vijay
    Agarwal, Neeraj
    Balasubramanian, Dorairajan
    Swarup, Ghanshyam
    [J]. INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE, 2007, 48 (04) : 1607 - 1614
  • [2] Adult-onset primary open-angle glaucoma caused by mutations in optineurin
    Rezaie, T
    Child, A
    Hitchings, R
    Brice, G
    Miller, L
    Coca-Prados, M
    Héon, E
    Krupin, T
    Ritch, R
    Kreutzer, D
    Crick, RP
    Sarfarazi, M
    [J]. SCIENCE, 2002, 295 (5557) : 1077 - 1079
  • [3] Optineurin links myosin VI to the Golgi complex and is involved in Golgi organization and exocytosis
    Sahlender, DA
    Roberts, RC
    Arden, SD
    Spudich, G
    Taylor, MJ
    Luzio, JP
    Kendrick-Jones, J
    Buss, F
    [J]. JOURNAL OF CELL BIOLOGY, 2005, 169 (02) : 285 - 295
  • [4] Optineurin negatively regulates TNFα-induced NF-κB activation by competing with NEMO for ubiquitinated RIP
    Zhu, Guozhi
    Wu, Chuan-Jin
    Zhao, Yongge
    Ashwell, Jonathan D.
    [J]. CURRENT BIOLOGY, 2007, 17 (16) : 1438 - 1443
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