A Comparative Study of Bone Formation Following Grafting with Different Ratios of Particle Dentin and Tricalcium Phosphate Combinations

被引：11

作者：

Jin, Seung-Chan ^{[1
]}

Kim, Su-Gwan ^{[1
]}

Oh, Ji-Su ^{[1
]}

Lee, Sook-Young ^{[1
]}

Jang, Eun-Sook ^{[1
]}

Piao, Zheng-Gang ^{[1
]}

Lim, Sung-Chul ^{[2
]}

Jeong, Mi-Ae ^{[3
]}

Kim, Jae-Sung ^{[1
]}

You, Jae-Seek ^{[1
]}

Park, Seung-Cheol ^{[1
]}

Cho, Young-Seung ^{[1
]}

Yang, Sung-Soo ^{[1
]}

Yu, Sun-Kyung ^{[4
]}

机构：

[1] Chosun Univ, Sch Dent, Dept Oral & Maxillofacial Surg, Kwangju 501759, South Korea

[2] Chosun Univ, Sch Med, Dept Pathol, Kwangju 501759, South Korea

[3] Kangwon Natl Univ, Dept Dent Hyg, Samcheok 245711, South Korea

[4] Chosun Univ, Sch Dent, Dept Anat & Orofacial Dev, Kwangju 501759, South Korea

来源：

JOURNAL OF BIOMEDICAL NANOTECHNOLOGY | 2013年 / 9卷 / 03期

关键词：

Hydroxyapatite; Tricalcium Phosphate; Bone Regeneration; Biomaterials; Graft; PERIODONTAL OSSEOUS DEFECTS; AUGMENTATION; CERAMICS; HYDROXYAPATITE; ALLOGRAFT; HUMANS; INDUCE;

D O I：

10.1166/jbn.2013.1505

中图分类号：

TB3 [工程材料学];

学科分类号：

0805 ; 080502 ;

摘要：

This study aimed to evaluate the bone regeneration relative to tooth powder and tricalcium phosphate (TCP) mixing ratios using the rabbit cranium defect model. The tooth powder was mixed with TCP in 1:1, 3:1, and 1:3 ratios, and the different ratios were implanted in the rabbit cranium defect for 4 and 8 weeks. Powders crystal structure evaluated using scanning electron microscopy (SEM), attenuated total reflectance-Fourier transform infrared spectroscopy (ATR-FTIR), and new bone formation (NBF) was analyzed using micro-computed tomography (CT) and histologic examination. NBF in the control group was restricted to the defect margins. More NBF was observed around the defect margins in the experimental groups compared with the control group. Specifically, active NBF was identified around the implant materials of the centrifugal part of the defect and defect margins in the 3:1 tooth powder:TCP group. Our results suggested that tooth powder and TCP may be useful in bone regeneration.

引用

页码：475 / 478

页数：4

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