Seronegative Hepatitis C Virus Infection in a Child Infected via Mother-to-Child Transmission

被引:13
|
作者
Larouche, Ariane [1 ,2 ]
Gaetan, Genevieve [1 ,2 ]
El-Bilali, Nabil [2 ,3 ]
Quesnel-Vallieres, Mathieu [1 ,2 ]
Martin, Steven R. [4 ,5 ]
Alvarez, Fernando [4 ,5 ]
Shoukry, Naglaa H. [3 ,6 ]
Soudeyns, Hugo [1 ,2 ,5 ]
机构
[1] CHU St Justine, Unite Immunopathologie Virale, Ctr Rech, Montreal, PQ, Canada
[2] Univ Montreal, Fac Med, Dept Microbiol & Immunol, Montreal, PQ H3C 3J7, Canada
[3] Hop St Luc, CRCHUM, Montreal, PQ H2X 1P1, Canada
[4] CHU St Justine, Div Gastroenterol Hepatol & Nutr, Montreal, PQ, Canada
[5] Univ Montreal, Fac Med, Dept Pediat, Montreal, PQ H3C 3J7, Canada
[6] Univ Montreal, Fac Med, Dept Med, Montreal, PQ H3C 3J7, Canada
基金
加拿大健康研究院;
关键词
QUASI-SPECIES EVOLUTION; VERTICAL TRANSMISSION; PERINATAL TRANSMISSION; LIVER-DISEASE; HCV INFECTION; ANTIBODY; PROGRESSION; VIREMIA; COHORT;
D O I
10.1128/JCM.00622-12
中图分类号
Q93 [微生物学];
学科分类号
071005 ; 100705 ;
摘要
Hepatitis C virus (HCV) infection typically leads to antibody response within weeks after primary infection. Here, we describe the case of a child infected with HCV by mother-to-child transmission who remained persistently seronegative despite the presence of high levels of circulating HCV RNA.
引用
收藏
页码:2515 / 2519
页数:5
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