Developing a SARS-CoV-2 Vaccine at Warp Speed

被引：62

作者：

O'Callaghan, Kevin P. ^{[1
]}

Blatz, Allison M. ^{[1
]}

Offit, Paul A. ^{[1
,2
]}

机构：

[1] Childrens Hosp Philadelphia, Div Infect Dis, 34th St & Civ Ctr Blvd,Abramson Res Bldg, Philadelphia, PA 19104 USA

[2] Univ Penn, Perelman Sch Med, Dept Pediat, Philadelphia, PA 19104 USA

来源：

JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION | 2020年 / 324卷 / 05期

关键词：

D O I：

10.1001/jama.2020.12190

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

This Viewpoint discusses the mechanisms of the 5 leading COVID-19 vaccine candidates-2 messenger RNA vaccines, 1 recombinant VSV vector product, and 2 replication-defective adenovirus vector approaches-and emphasizes the need to demonstrate safety as well as efficacy to facilitate broad uptake by the public.

引用

页码：437 / 438

页数：2

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