NCCN Guidelines Insights: Chronic Lymphocytic Leukemia/Small Lymphocytic Lymphoma, Version 2.2019

被引：31

作者：

Wierda, William G. ^{[1
]}

Byrd, John C. ^{[2
,3
]}

Abramson, Jeremy S. ^{[4
]}

Bilgrami, Syed F. ^{[5
]}

Bociek, Greg ^{[6
]}

Brander, Danielle ^{[7
]}

Brown, Jennifer ^{[8
]}

Chanan-Khan, Asher A. ^{[9
]}

Chavez, Julio C. ^{[10
]}

Coutre, Steve E. ^{[11
]}

Davis, Randall S. ^{[12
]}

Fletcher, Christopher D. ^{[13
]}

Hill, Brian ^{[14
,15
]}

Kahl, Brad S. ^{[16
,17
]}

Kamdar, Manali ^{[18
]}

Kaplan, Lawrence D. ^{[19
]}

Khan, Nadia ^{[20
]}

Kipps, Thomas J. ^{[21
]}

Ma, Shuo ^{[22
]}

Malek, Sami ^{[23
]}

Mato, Anthony ^{[24
]}

Mosse, Claudio ^{[25
]}

Neppalli, Vishala T. ^{[26
]}

Shadman, Mazyar ^{[27
]}

Siddiqi, Tanya ^{[28
]}

Stephens, Deborah ^{[29
]}

Wagner, Nina ^{[30
]}

Dwyer, Mary A. ^{[31
]}

Sundar, Hema ^{[31
]}

机构：

[1] Univ Texas MD Anderson Canc Ctr, Houston, TX 77030 USA

[2] Ohio State Univ, Ctr Comprehens Canc, James Canc Hosp, Columbus, OH 43210 USA

[3] Ohio State Univ, Solove Res Inst, Columbus, OH 43210 USA

[4] Massachusetts Gen Hosp, Canc Ctr, Boston, MA 02114 USA

[5] Smilow Canc Hosp, Yale Canc Ctr, New Haven, CT USA

[6] Fred & Pamela Buffett Canc Ctr, Omaha, NE USA

[7] Duke Canc Inst, Durham, NC USA

[8] Dana Farber Brigham & Womens Canc Ctr, Boston, MA USA

[9] Mayo Clin, Canc Ctr, Rochester, MN USA

[10] H Lee Moffitt Canc Ctr & Res Inst, Tampa, FL USA

[11] Stanford Canc Inst, Stanford, CA USA

[12] Univ Alabama Birmingham, Comprehens Canc Ctr, Birmingham, AL USA

[13] Univ Wisconsin, Carbone Canc Ctr, Madison, WI 53706 USA

[14] Univ Hosp Seidman Canc Ctr, Case Comprehens Canc Ctr, Cleveland, OH USA

[15] Cleveland Clin, Taussig Canc Inst, Cleveland, OH 44106 USA

[16] Barnes Jewish Hosp, Siteman Canc Ctr, St Louis, MO 63110 USA

[17] Washington Univ, Sch Med, St Louis, MO 63130 USA

[18] Univ Colorado, Canc Ctr, Boulder, CO 80309 USA

[19] UCSF Helen Diller Family Comprehens Canc Ctr, San Francisco, CA USA

[20] Fox Chase Canc Ctr, 7701 Burholme Ave, Philadelphia, PA 19111 USA

[21] Univ Calif San Diego, Moores Canc Ctr, San Diego, CA USA

[22] Northwestern Univ, Robert H Lurie Comprehens Canc Ctr, Evanston, IL 60208 USA

[23] Univ Michigan, Rogel Canc Ctr, Ann Arbor, MI 48109 USA

[24] Mem Sloan Kettering Canc Ctr, 1275 York Ave, New York, NY 10021 USA

[25] Vanderbilt Ingram Canc Ctr, Nashville, TN USA

[26] Roswell Pk Comprehens Canc Ctr, Buffalo, NY USA

[27] Fred Hutchinson Canc Res Ctr, Seattle Canc Care Alliance, 1124 Columbia St, Seattle, WA 98104 USA

[28] City Hope Natl Med Ctr, 1500 E Duarte Rd, Duarte, CA 91010 USA

[29] Univ Utah, Huntsman Canc Inst, Salt Lake City, UT 84112 USA

[30] Sidney Kimmel Comprehens Canc Ctr Johns Hopkins, Baltimore, MD USA

[31] Natl Comprehens Canc Network, Plymouth Meeting, PA USA

来源：

JOURNAL OF THE NATIONAL COMPREHENSIVE CANCER NETWORK | 2019年 / 17卷 / 01期

关键词：

B-CELL LYMPHOMA; PHASE I-II; RICHTER TRANSFORMATION; HODGKIN LYMPHOMA; FRACTIONATED CYCLOPHOSPHAMIDE; LIPOSOMAL DAUNORUBICIN; RETROSPECTIVE ANALYSIS; CLL; FLUDARABINE; CYTARABINE;

D O I：

10.6004/jnccn.2019.0002

中图分类号：

R73 [肿瘤学];

学科分类号：

100214 ;

摘要：

Chronic lymphocytic leukemia (CLL) is generally characterized by an indolent disease course. Histologic transformation (also known as Richter's transformation) to more aggressive lymphomas, such as diffuse large B-cell lymphoma or Hodgkin lymphoma, occurs in approximately 2% to 10% of patients and is associated with a poor prognosis. These NCCN Guidelines Insights discuss the recommendations for the diagnosis and management of patients with histologic transformation.

引用

页码：12 / 20

页数：9

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