H-NS and RpoS regulate emergence of Lac Ara(+) mutants of Escherichia coli MCS2

被引:41
|
作者
GomezGomez, JM [1 ]
Blazquez, J [1 ]
Baquero, F [1 ]
Martinez, JL [1 ]
机构
[1] CSIC,BANCO CELULAS,CTR NACL BIOTECHNOL,E-28049 MADRID,SPAIN
关键词
D O I
10.1128/jb.179.14.4620-4622.1997
中图分类号
Q93 [微生物学];
学科分类号
071005 ; 100705 ;
摘要
Two master growth-phase regulatory proteins, H-NS and sigma(S), are involved in the formation of araB-lacZ fusion clones of Escherichia coli MCS2. The stationary-phase sigma factor RpoS is strictly required for the appearance of such mutants, whereas the histone-like protein H-NS represses their emergence. Our results support the idea that genetic changes leading do adaptive mutation in this model system are regulated by physiological signal transduction networks.
引用
收藏
页码:4620 / 4622
页数:3
相关论文
共 50 条
  • [1] rpoS function is essential for bgl silencing caused by C-terminally truncated H-NS in Escherichia coli
    Ohta, T
    Ueguchi, C
    Mizuno, T
    JOURNAL OF BACTERIOLOGY, 1999, 181 (20) : 6278 - 6283
  • [2] Interplay between global regulators of Escherichia coli:: effect of RpoS, Lrp and H-NS on transcription of the gene osmC
    Bouvier, J
    Gordia, S
    Kampmann, G
    Lange, R
    Hengge-Aronis, R
    Gutierrez, C
    MOLECULAR MICROBIOLOGY, 1998, 28 (05) : 971 - 980
  • [3] The nucleoid protein H-NS facilitates chromosome DNA replication in Escherichia coli dnaA mutants
    Katayama, T
    Takata, M
    Sekimizu, K
    JOURNAL OF BACTERIOLOGY, 1996, 178 (19) : 5790 - 5792
  • [4] SlyA and H-NS regulate transcription of the Escherichia coli K5 capsule gene cluster, and expression of slyA in Escherichia coli is temperature-dependent, positively autoregulated, and independent of H-NS
    Corbett, David
    Bennett, Hayley J.
    Askar, Hamdia
    Green, Jeffrey
    Roberts, Ian S.
    JOURNAL OF BIOLOGICAL CHEMISTRY, 2007, 282 (46) : 33326 - 33335
  • [5] Overexpression of the third H-NS paralogue H-NS2 compensates fitness loss in hns mutants of the enteroaggregative Escherichia coli strain 042
    Prieto, A.
    Bernabeu, M.
    Falgenhauer, L.
    Chakraborty, T.
    Huttener, M.
    Juarez, A.
    SCIENTIFIC REPORTS, 2020, 10 (01)
  • [6] The Escherichia coli SOS gene sbmC is regulated by H-NS and RpoS during the SOS induction and stationary growth phase
    Oh, TJ
    Jung, IL
    Kim, IG
    BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, 2001, 288 (04) : 1052 - 1058
  • [7] Overexpression of the third H-NS paralogue H-NS2 compensates fitness loss in hns mutants of the enteroaggregative Escherichia coli strain 042
    A. Prieto
    M. Bernabeu
    L. Falgenhauer
    T. Chakraborty
    M. Hüttener
    A. Juárez
    Scientific Reports, 10
  • [8] The Role of Escherichia coli Protein H-NS in Chromosome Integrity
    Pina, Cara
    Lovett, Susan
    FASEB JOURNAL, 2015, 29
  • [9] The role of RpoS, H-NS and AcP on the pH-dependent OmpC and OmpF porin expressions of Escherichia coli at different pH
    Darcan, Cihan
    Oezkanca, Resit
    Idil, Oender
    AFRICAN JOURNAL OF BIOTECHNOLOGY, 2009, 8 (09): : 1845 - 1854
  • [10] ANALYSIS OF TRANSCRIPTIONAL REPRESSION BY ESCHERICHIA-COLI H-NS PROTEIN
    RIMSKY, S
    WILLIAMS, R
    KOTLARZ, D
    BUC, H
    JOURNAL OF CELLULAR BIOCHEMISTRY, 1995, : 115 - 115