Physics Controversies in Proton Therapy

被引：130
作者：
Engelsman, Martijn [1 ]
Schwarz, Marco [2 ]
Dong, Lei [3 ]
机构：
[1] Delft Univ Technol, Delft, Netherlands
[2] ATreP Agenzia Prov Protonterapia, Trento, Italy
[3] Scripps Proton Therapy Ctr, San Diego, CA USA
来源：
SEMINARS IN RADIATION ONCOLOGY | 2013年 / 23卷 / 02期
关键词：
CELL-LUNG-CANCER; MONTE-CARLO SIMULATIONS; IN-VIVO VERIFICATION; COMPUTED-TOMOGRAPHY; RADIATION-THERAPY; RANGE UNCERTAINTIES; BEAM DELIVERY; RADIOTHERAPY; SYSTEM; MOTION;
D O I：
10.1016/j.semradonc.2012.11.003
中图分类号：
R73 [肿瘤学];
学科分类号：
100214 ;
摘要：
The physical characteristics of proton beams are appealing for cancer therapy. The rapid increase in operational and planned proton therapy facilities may suggest that this technology is a "plug-and-play" valuable addition to the arsenal of the radiation oncologist and medical physicist. In reality, the technology is still evolving, so planning and delivery of proton therapy in patients face many practical challenges. This review article discusses the current status of proton therapy treatment planning and delivery techniques, indicates current limitations in dealing with range uncertainties, and proposes possible developments for proton therapy and supplementary technology to try to realize the actual potential of proton therapy. Semin Radiat Oncol 23:88-96 (C) 2013 All rights reserved.
引用
收藏
页码：88 / 96
页数：9
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