Facile synthesis of water-dispersible Cu2O nanocrystal-reduced graphene oxide hybrid as a promising cancer therapeutic agent

被引:49
|
作者
Hou, Chengyi [1 ,2 ]
Quan, Haocheng [1 ,2 ]
Duan, Yourong [3 ]
Zhang, Qinghong [1 ]
Wang, Hongzhi [1 ]
Li, Yaogang [2 ]
机构
[1] Donghua Univ, Coll Mat Sci & Engn, State Key Lab Modificat Chem Fibers & Polymer Mat, Shanghai 201620, Peoples R China
[2] Donghua Univ, Coll Mat Sci & Engn, Engn Res Ctr Adv Glasses Mfg Technol, Shanghai 201620, Peoples R China
[3] Shanghai Jiao Tong Univ, Sch Med, Renji Hosp, Shanghai Canc Inst, Shanghai 200032, Peoples R China
关键词
ANTICANCER ACTIVITY; VISIBLE-LIGHT; LASER; NANOPARTICLES; DAMAGE; COMPOSITE; NANOCAGES; REMOVAL; GREEN; CELLS;
D O I
10.1039/c2nr32938g
中图分类号
O6 [化学];
学科分类号
0703 ;
摘要
We report a Cu2O nanocrystal-reduced graphene oxide hybrid that is dispersible in water and has anticancer activity under both visible and near-infrared light irradiation. In contrast to the highly efficient killing of both normal and cancer cells initiated by the photothermal effect, the photocatalytic effect of this material results in the selective killing of cancer cells under visible light irradiation. These results have implications for safe and widely applicable cancer therapy agents.
引用
收藏
页码:1227 / 1232
页数:6
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