Structural Modifications that Alter the P-Glycoprotein Efflux Properties of Compounds

被引：179

作者：

Hitchcock, Stephen A. ^{[1
]}

机构：

[1] Envoy Therapeut, Jupiter, FL 33458 USA

来源：

JOURNAL OF MEDICINAL CHEMISTRY | 2012年 / 55卷 / 11期

关键词：

BLOOD-BRAIN-BARRIER; CENTRAL-NERVOUS-SYSTEM; IN-VITRO; DRUG DISCOVERY; SPECIES-DIFFERENCES; THERAPEUTIC AGENTS; TRANSPORT FUNCTION; CNS; PERMEABILITY; PENETRATION;

D O I：

10.1021/jm201136z

中图分类号：

R914 [药物化学];

学科分类号：

100701 ;

摘要：

[No abstract available]

引用

页码：4877 / 4895

页数：19

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