Advances in understanding respiratory syncytial virus infection in airway epithelial cells and consequential effects on the immune response

被引：49
作者：
Lay, Margarita K. [1 ]
Gonzalez, Pablo A. [1 ]
Leon, Miguel A. [1 ]
Cespedes, Pablo F. [1 ]
Bueno, Susan M. [1 ,3 ]
Riedel, Claudia A. [4 ,5 ]
Kalergis, Alexis M. [1 ,2 ,3 ]
机构：
[1] Pontificia Univ Catolica Chile, Millennium Inst Immunol & Immunotherapy, Dept Mol Genet & Microbiol, Fac Ciencias Biol, Santiago 8331010, Chile
[2] Pontificia Univ Catolica Chile, Fac Med, Dept Reumatol, Santiago 8331010, Chile
[3] INSERM, U1064, Nantes, France
[4] Univ Andres Bello, Fac Ciencias Biol, Dept Ciencias Biol, Millennium Inst Immunol & Immunotherapy,Lab Biol, Santiago, Chile
[5] Univ Andres Bello, Fac Med, Santiago, Chile
来源：
MICROBES AND INFECTION | 2013年 / 15卷 / 03期
关键词：
RSV; Airway epithelial cells; Entry; Replication cycle; Immune response; Thymic stromal lymphopoietin; THYMIC STROMAL LYMPHOPOIETIN; MATRIX PROTEIN; G-GLYCOPROTEIN; IN-VITRO; RNA REPLICATION; INFLUENZA-VIRUS; TRAILER REGION; MESSENGER-RNA; LIPID RAFTS; P-PROTEIN;
D O I：
10.1016/j.micinf.2012.11.012
中图分类号：
R392 [医学免疫学]; Q939.91 [免疫学];
学科分类号：
100102 ;
摘要：
This article reviews aspects of respiratory syncytial virus (RSV) infection in airway epithelial cells (AECs), including cytopathogenesis, entry, replication and the induction of immune response to the virus, including a new role for thymic stromal lymphopoietin in RSV immunopathology. (C) 2012 Institut Pasteur. Published by Elsevier Masson SAS. All rights reserved.
引用
收藏
页码：230 / 242
页数：13
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