Warning of high-flux hemodialysis

被引：5

作者：

Takenaka, T ^{[1
]}

Kobayashi, K ^{[1
]}

Suzuki, H ^{[1
]}

机构：

[1] Saitama Med Coll, Dept Med, Moroyama, Saitama 3500451, Japan

来源：

RENAL FAILURE | 2001年 / 23卷 / 06期

关键词：

blood pressure; oncotic pressure; plasma osmolarity; plasma refilling; ultrafiltration;

D O I：

10.1081/JDI-100108193

中图分类号：

R5 [内科学]; R69 [泌尿科学（泌尿生殖系疾病）];

学科分类号：

1002 ; 100201 ;

摘要：

In order to estimate the influence of flux on plasma refilling during hemodialysis (HD), prospective crossover studies were performed in 10 HD patients with low-flux and high-flux dialyzers. Hematocrit was continuously monitored to assess changes in blood volume. In addition, plasma osmolarity and total protein concentration were measured. Intradialytic reductions in body weight (-5 +/-1 vs -5 +/-1%) and plasma osmolarity (-5 +/-1 vs -5 +/-1%) were similar in both conditions. Although mean blood pressure remained unchanged in either state, the decrease in blood volume was larger in high-flux HD (-13 +/-2 vs -10 +/-2%, p < 0.05). In spite of greater contraction in blood volume during high-flux HD, total proteins were increased equally between low-flux and high-flux HD (11 +/-4 vs 11 +/-4%). Our data that although high-flux HD failed to induce significant drops in blood pressure, it elicited greater magnitude of decreases in blood volume, implicate the judicious application of highflux HD.

引用

页码：819 / 825

页数：7

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