Randomised β-carotene supplementation and incidence of cancer and cardiovascular disease in women:: is the association modified by baseline plasma level?

被引：11
作者：
Lee, IM
Cook, NR
Manson, JE
Buring, JE
机构：
[1] Brigham & Womens Hosp, Dept Med, Div Prevent Med, Boston, MA 02215 USA
[2] Harvard Univ, Sch Med, Dept Ambulatory Care & Prevent, Boston, MA 02215 USA
[3] Brigham & Womens Hosp, Dept Med, Channing Lab, Boston, MA 02215 USA
[4] Harvard Sch Publ Hlth, Dept Epidemiol, Boston, MA 02115 USA
来源：
BRITISH JOURNAL OF CANCER | 2002年 / 86卷 / 05期
关键词：
beta-carotene; cancer; cardiovascular disease; epidemiology;
D O I：
10.1038/sj.bjc.6600147
中图分类号：
R73 [肿瘤学];
学科分类号：
100214 ;
摘要：
In a nested case-control study of 5 13 women with cancer, l 30 with cardiovascular disease and equal numbers of controls, we found no effect of randomised beta-carotene on risk of cancer or cardiovascular disease within any quartile of baseline plasma beta-carotene, nor was there a trend across quartiles (P for trend 0.15 and 0.62, respectively). (C) 2002 Cancer Research UK.
引用
收藏
页码：698 / 701
页数：4
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