Spurious Elevation of Glucose Concentration during Administration of High Dose of Ascorbic Acid in a Patient with Type 2 Diabetes on Hemodialysis

被引：10

作者：

Kim, Soo Kyoung ^{[1
,4
]}

Hahm, Jong Ryeal ^{[1
,4
]}

Kim, Ho-Su ^{[1
]}

Kim, Sungsu ^{[1
]}

Jung, Tae Sik ^{[1
,4
]}

Jung, Jung Hwa ^{[1
]}

Lee, Hye Ryun ^{[2
]}

Kim, Deok Ryong ^{[3
]}

机构：

[1] Gyeongsang Natl Univ, Sch Med, Dept Internal Med, Jinju 660702, South Korea

[2] Gyeongsang Natl Univ, Sch Med, Dept Lab Med, Jinju 660702, South Korea

[3] Gyeongsang Natl Univ, Sch Med, Dept Biochem, Jinju 660702, South Korea

[4] Gyeongsang Natl Univ, Sch Med, Inst Hlth Sci, Jinju 660702, South Korea

来源：

YONSEI MEDICAL JOURNAL | 2013年 / 54卷 / 05期

基金：

新加坡国家研究基金会;

关键词：

Self-monitoring of blood glucose; ascorbic acid; hypoglycemia; BLOOD-GLUCOSE; PERITONEAL-DIALYSIS; TEST STRIPS; ICODEXTRIN;

D O I：

10.3349/ymj.2013.54.5.1289

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

We describe herein a case of life-threatening hypoglycemia due to spurious elevation of glucose concentration during the administration of ascorbic acid in a type 2 diabetic patient. A 31-year-old female was admitted for proliferative diabetic retinopathy treatment and prescribed high dose ascorbic acid. During hospitalization, she suddenly lost her consciousness and her glucose concentration was 291 mg/dL, measured using self-monitoring blood glucose (SMBG) device, while venous blood glucose concentration was 12 mg/dL. After intravenous injection of 50% glucose solution, the patient became alert. We reasoned that glucose measurement by SMBG device was interfered by ascorbic acid. Physicians should be aware of this interference; high dose ascorbic acid may cause spurious elevation of glucose concentration when measuring with SMBG devices.

引用

页码：1289 / 1292

页数：4

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