Simultaneous Determination of Epinephrine and Tyrosine Using a Glassy Carbon Electrode Amplified with ZnO-Pt/CNTs Nanocomposite

被引：14
作者：
Samadzadeha, Ali [1 ]
Shcikhshoaie, Iran [1 ]
Karimi-Maleh, Hassan [2 ]
机构：
[1] Shahid Bahonar Univ, Dept Chem, Kerman, Iran
[2] Quchan Univ Technol, Dept Chem Engn, Lab Nanotechnol, Quchan, Iran
来源：
CURRENT ANALYTICAL CHEMISTRY | 2019年 / 15卷 / 02期
关键词：
Epinephrine; tyrosine; ZnO-Pt/CNTs nanocomposite; electrochemical sensors; carbon electrode; biological compounds; SENSITIVE VOLTAMMETRIC DETERMINATION; NANOTUBES PASTE ELECTRODE; REDUCED GRAPHENE OXIDE; ELECTROCHEMICAL SENSOR; IONIC LIQUID; ASCORBIC-ACID; URIC-ACID; ZNO/CNTS NANOCOMPOSITE; N-ACETYLCYSTEINE; DNA BIOSENSOR;
D O I：
10.2174/1573411014666180313115001
中图分类号：
O65 [分析化学];
学科分类号：
070302 ; 081704 ;
摘要：
Background: Simultaneous analysis of epinephrine and tyrosine as two effective and important biological compounds in human blood and urine samples are very important for the investigation of human health. Objective: In this research, a highly effective voltammetric sensor fabricated for simultaneous analysis of epinephrine and tyrosine. The sensor was fabricated by the modification of glassy carbon electrode with ZnO-Pt/CNTs nanocomposite (ZnO-Pt/CNTs/GCE). The synthesized nanocomposite was characterized by SEM method. The ZnO-Pt/CNTs/GCE showed two separated oxidation signals at potential similar to 220 mV and 700 mV for epinephrine and tyrosine, respectively. Also, we detected linear dynamic ranges 0.5-250.0 mu M and 1.0-220 mu M with a limit of detections 0.1 mu M and 0.5 mu M for the determination of epinephrine and tyrosine, respectively. The ZnO-Pt/CNTs/GCE was used for the determination of epinephrine and tyrosine in blood serum and human urine samples.
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收藏
页码：166 / 171
页数：6
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