Regio- and stereoselective intermolecular carbolithiation reactions

被引：7

作者：

Marsico, G. ^{[1
]}

Scafato, P. ^{[1
]}

Belviso, S. ^{[1
]}

Superchi, S. ^{[1
]}

机构：

[1] Univ Basilicata, Dipartimento Sci, Via Ateneo Lucano 10, I-8510 Patenza, Italy

来源：

RSC ADVANCES | 2020年 / 10卷 / 54期

关键词：

ENANTIOSELECTIVE CARBOLITHIATION; STYRENE DERIVATIVES; INTRAMOLECULAR CARBOLITHIATION; ORGANOLITHIUM ADDITIONS; CONFIGURATIONAL STABILITY; CINNAMYL DERIVATIVES; ARYL MIGRATION; ROUTE; ALKYLATION; ACCESS;

D O I：

10.1039/d0ra06101h

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

Theinter-molecular carbolithiation of unfunctionalized and functionalized alkenes, followed by electrophile trapping, provides a versatile and useful tool for the construction of complex molecular systems, allowing the simultaneous creation of up to two novel carbon-carbon or carbon-heteroatom bonds. In this review a full overview oninter-molecular carbolithiation processes is reported, with a main focus on the chemo-, regio- and stereo-control of the reaction and on the strategies for asymmetric processes.

引用

页码：32581 / 32601

页数：21

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