Theanine improves stress resistance in Caenorhabditis elegans

被引：22

作者：

Gong Yushun ^{[1
]}

Luo Yunfeng ^{[3
]}

Huang Jian-an ^{[1
]}

Zhang Jianwei ^{[2
]}

Peng Yuxuan ^{[2
]}

Liu Zhonghua ^{[2
,4
]}

Zhao Baolu ^{[3
]}

机构：

[1] Hunan Agr Univ, Minist Educ, Key Lab Tea Sci, Changsha 410128, Hunan, Peoples R China

[2] Hunan Agr Univ, Natl Res Ctr Engn Technol Utilizat Bot Funct Ingr, Changsha 410128, Hunan, Peoples R China

[3] Chinese Acad Sci, Inst Biophys, State Key Lab Brain & Cognit Sci, Beijing 100101, Peoples R China

[4] Tsinghua Univ, Dept Chem, Key Lab Bioorgan Phosphorus Chem & Chem Biol, Beijing 100084, Peoples R China

来源：

JOURNAL OF FUNCTIONAL FOODS | 2012年 / 4卷 / 04期

基金：

美国国家科学基金会;

关键词：

Theanine; Caenorhabditis elegans; Stress resistance; Heat shock protein; UNIQUE AMINO-ACID; INCREASE LIFE-SPAN; TEA LEAVES; RATS; PATHWAYS; MEMORY; MICE;

D O I：

10.1016/j.jff.2012.04.005

中图分类号：

TS2 [食品工业];

学科分类号：

0832 ;

摘要：

The beneficial effects of theanine in tea are reported on many aspects. Here we report that theanine can extend nematode Caenorhabditis elegans lifespan under stress. Theanine (100 mg/mL) significantly increased the mean longevity of C. elegans by 12.8% and 21.3% under heat stress and oxidative stress, respectively. However, theanine treatment did not increase survival of C. elegans under normal culture condition. Further studies showed that theanine mediated lifespan extension under heat stress was involved in heat shock protein-16.2 (HSP-16.2) up-regulating expression. (C) 2012 Elsevier Ltd. All rights reserved.

引用

页码：988 / 993

页数：6

共 50 条

[21] Knockdown of LMW-PTP enhances stress resistance in Caenorhabditis elegans
Zhou, Lin
Wang, Lu
Bai, Shuju
Xing, Shu
Li, Wannan
Ma, Junfeng
Fu, Xueqi
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES, 2018, 113 : 1015 - 1023
[22] GLB-13 is associated with oxidative stress resistance in caenorhabditis elegans
Ren, Changhong
Li, Yuan
Han, Rongrong
Gao, Dawen
Li, Weiguang
Shi, Jinping
Hoogewijs, David
Braeckman, Bart P.
De Henau, Sasha
Lu, Yiming
Qu, Wubin
Gao, Yan
Wu, Yonghong
Li, Zhihui
Liu, Huqi
Wang, Zhaoyan
Zhang, Chenggang
IUBMB LIFE, 2013, 65 (05) : 423 - 434
[23] Polygonatum cyrtonema HuaPolysaccharides with Antiaging and Stress Resistance Efficacies in Caenorhabditis elegans
Wang, Wei
Yang, Ying
Hou, Ting-ting
Yi, Shan-yong
Chen, Yan-jun
Li, Guo-si
Chen, Cun-wu
Han, Bang-xing
Ke, Jia-ping
Liu, Dong
Gao, Lei-lei
JOURNAL OF FOOD BIOCHEMISTRY, 2023, 2023
[24] Evaluation of the influence of fullerenol on aging and stress resistance using Caenorhabditis elegans
Cong, Wenshu
Wang, Peng
Qu, Ying
Tang, Jinglong
Bai, Ru
Zhao, Yuliang
Chen, Chunying
Bi, Xiaolin
BIOMATERIALS, 2015, 42 : 78 - 86
[25] Photodynamic treatment increases the lifespan and oxidative stress resistance of Caenorhabditis elegans
Nguyen, Uyen Tran Tu
Youn, Esther
Le, Tram Anh Ngoc
Ha, Ngoc Minh
Tran, Son Hung
Lee, Sohyun
Cha, Jin Wook
Park, Jin-Soo
Kwon, Hak Cheol
Kang, Kyungsu
FREE RADICAL BIOLOGY AND MEDICINE, 2024, 221 : 98 - 110
[26] Effects of Orange Extracts on Longevity, Healthspan, and Stress Resistance in Caenorhabditis elegans
Wang, Jing
Deng, Na
Wang, Hong
Li, Tong
Chen, Ling
Zheng, Bisheng
Liu, Rui Hai
MOLECULES, 2020, 25 (02):
[27] Longevity and resistance to stress correlate with DNA repair capacity in Caenorhabditis elegans
Hyun, Moonjung
Lee, Jihyun
Lee, Kyungjin
May, Alfred
Bohr, Vilhelm A.
Ahn, Byungchan
NUCLEIC ACIDS RESEARCH, 2008, 36 (04) : 1380 - 1389
[28] Using stress resistance to isolate novel longevity mutations in Caenorhabditis elegans
Sampayo, JN
Jenkins, NL
Lithgow, GJ
MOLECULAR AND CELLULAR GERONTOLOGY, 2000, 908 : 324 - 326
[29] A deuterohemin peptide extends lifespan and increases stress resistance in Caenorhabditis elegans
Guan, Shuwen
Li, Pengfei
Luo, Jing
Li, Yuanyuan
Huang, Lei
Wang, Guan
Zhu, Limin
Fan, Hongkuan
Li, Wei
Wang, Liping
FREE RADICAL RESEARCH, 2010, 44 (07) : 813 - 820
[30] Heritable Transmission of Stress Resistance by High Dietary Glucose in Caenorhabditis elegans
Tauffenberger, Arnaud
Parker, J. Alex
PLOS GENETICS, 2014, 10 (05):

← 1 2 3 4 5 →