Neogrifolin derivatives possessing anti-oxidative activity from the mushroom Albatrellus ovinus

被引：75
作者：
Nukata, M
Hashimoto, T
Yamamoto, I
Iwasaki, N
Tanaka, M
Asakawa, Y [1 ]
机构：
[1] Tokushima Bunri Univ, Fac Pharmaceut Sci, Yamashiro, Tokushima 7708514, Japan
[2] Kurashiki Sakuyo Univ, Fac Food Culture, Kurashiki, Okayama 7100290, Japan
来源：
PHYTOCHEMISTRY | 2002年 / 59卷 / 07期
关键词：
mushroom; Scutigeraceae; Albatrellus ovinus; neogrifolin derivatives; 3-hydroxyneogrifolin; 1-formylneogrifolin; 1-formyl-3-hydroxyneogrifolin; two-dimensional NMR; antioxidative activity;
D O I：
10.1016/S0031-9422(02)00050-X
中图分类号：
Q5 [生物化学]; Q7 [分子生物学];
学科分类号：
071010 ; 081704 ;
摘要：
Three neogrifolin derivatives, 3-hydroxyneogrifolin, 1-formylneogrifolin and 1-formyl-3-hydroxyneogrifolin along with grifolin and neogrifolin were isolated from the Japanese mushroom Albatrellus ovinas belonging to Scutigeraceae. Their structures were established by a combination of two-dimensional NMR spectroscopic analyses and by chemical synthesis. 3-Hydroxyneogrifolin and 1-formyl-3-hydroxy-neogrifolin showed more potent antioxidative activity properties than either a-tocopherol or BHA. (C) 2002 Elsevier Science Ltd. All rights reserved.
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页码：731 / 737
页数：7
相关论文
共 18 条
[1]   CRYPTOPORIC ACIDS A-G, DRIMANE-TYPE SESQUITERPENOID ETHERS OF ISOCITRIC ACID FROM THE FUNGUS CRYPTOPORUS-VOLVATUS [J].
ASAKAWA, Y ;
HASHIMOTO, T ;
MIZUNO, Y ;
TORI, M ;
FUKAZAWA, Y .
PHYTOCHEMISTRY, 1992, 31 (02) :579-592
[2]  
Asakawa Yoshinori, 1993, P319
[3]   5 10-PHENYL-[11]-CYTOCHALASANS FROM A DALDINIA FUNGAL SPECIES [J].
BUCHANAN, M ;
HASHIMOTO, T ;
ASAKAWA, Y .
PHYTOCHEMISTRY, 1995, 40 (01) :135-140
[4]   Cytochalasins from a Daldinia sp of fungus [J].
Buchanan, MS ;
Hashimoto, T ;
Asakawa, Y .
PHYTOCHEMISTRY, 1996, 41 (03) :821-828
[5]   A 10-phenyl-[11]-cytochalasan from a species of Daldinia [J].
Buchanan, MS ;
Hashimoto, T ;
Takaoka, S ;
Kan, Y ;
Asakawa, Y .
PHYTOCHEMISTRY, 1996, 42 (01) :173-176
[6]  
Ding H., 1982, ZHONG GUO YAO YUN BA, P1
[7]   CRYPTOPORIC ACID-A AND ACID-B, NOVEL BITTER DRIMANE SESQUITERPENOID ETHERS OF ISOCITRIC ACID, FROM THE FUNGUS CRYPTOPORUS-VOLVATUS [J].
HASHIMOTO, T ;
TORI, M ;
MIZUNO, Y ;
ASAKAWA, Y .
TETRAHEDRON LETTERS, 1987, 28 (50) :6303-6304
[8]   THE SUPEROXIDE RELEASE INHIBITORS, CRYPTOPORIC ACID-C, ACID-D, AND ACID-E - DIMERIC DRIMANE SESQUITERPENOID ETHERS OF ISOCITRIC ACID FROM THE FUNGUS CRYPTOPORUS-VOLVATUS [J].
HASHIMOTO, T ;
TORI, M ;
MIZUNO, Y ;
ASAKAWA, Y ;
FUKAZAWA, Y .
JOURNAL OF THE CHEMICAL SOCIETY-CHEMICAL COMMUNICATIONS, 1989, (04) :258-259
[9]  
Hashimoto T, 1998, HETEROCYCLES, V47, P1067
[10]  
HASHIMOTO T, 1988, T MYCOL SOC JAPAN, V29, P281
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