Nanotechnology in dentistry: prevention, diagnosis, and therapy

被引:75
作者
Abou Neel, Ensanya Ali [1 ,2 ,3 ]
Bozec, Laurent [3 ]
Perez, Roman A. [4 ,5 ,6 ]
Kim, Hae-Won [4 ,5 ,6 ,7 ]
Knowles, Jonathan C. [3 ,5 ,6 ]
机构
[1] King Abdulaziz Univ, Fac Dent, Dept Operat Dent, Div Biomat, Jeddah 21589, Saudi Arabia
[2] Tanta Univ, Fac Dent, Biomat Dept, Tanta, Egypt
[3] UCL Eastman Dent Inst, Biomat & Tissue Engn, London, England
[4] Dankook Univ, ITREN, Cheonan, South Korea
[5] Dankook Univ, Dept Nanobiomed Sci, Cheonan, South Korea
[6] Dankook Univ, Plus NBM Global Res Ctr Regenerat Med BK21, Cheonan, South Korea
[7] Dankook Univ, Coll Dent, Dept Biomat Sci, Cheonan, South Korea
基金
新加坡国家研究基金会;
关键词
nanotechnology; nanointerfaces; biofilm-related oral diseases; tissue engineering; drug delivery; toxicity; C-REACTIVE PROTEIN; PULP STEM-CELLS; BONE MORPHOGENETIC PROTEIN-2; CALCIUM-PHOSPHATE NANOPARTICLES; HUMAN OSTEOGENIC PROTEIN-1; COATED GOLD NANOPARTICLES; OF-THE-ART; IN-VITRO; QUANTUM DOTS; ALVEOLAR BONE;
D O I
10.2147/IJN.S86033
中图分类号
TB3 [工程材料学];
学科分类号
0805 ; 080502 ;
摘要
Nanotechnology has rapidly expanded into all areas of science; it offers significant alternative ways to solve scientific and medical questions and problems. In dentistry, nanotechnology has been exploited in the development of restorative materials with some significant success. This review discusses nanointerfaces that could compromise the longevity of dental restorations, and how nanotechnolgy has been employed to modify them for providing long-term successful restorations. It also focuses on some challenging areas in dentistry, eg, oral biofilm and cancers, and how nanotechnology overcomes these challenges. The recent advances in nanodentistry and innovations in oral health-related diagnostic, preventive, and therapeutic methods required to maintain and obtain perfect oral health, have been discussed. The recent advances in nanotechnology could hold promise in bringing a paradigm shift in dental field. Although there are numerous complex therapies being developed to treat many diseases, their clinical use requires careful consideration of the expense of synthesis and implementation.
引用
收藏
页码:6371 / 6394
页数:24
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