Interaction of Cy3 dye with CCG and its application for BSA detection

被引：15

作者：

Li, Haiju ^{[1
]}

Liu, Fengyu ^{[2
]}

Han, Jingfeng ^{[3
]}

Cai, Mingzhu ^{[1
]}

Sun, Shiguo ^{[1
]}

Fan, Jiangli ^{[1
]}

Song, Fengling ^{[1
]}

Peng, Xiaojun ^{[1
]}

机构：

[1] Dalian Univ Technol, State Key Lab Fine Chem, Dalian 116012, Peoples R China

[2] Dalian Univ Technol, Sch Chem, Dalian 116023, Peoples R China

[3] Dalian Inst Chem Phys, Dalian Natl Lab Clean Energy, Div Solar Energy, Dalian 116023, Peoples R China

来源：

JOURNAL OF MATERIALS CHEMISTRY B | 2013年 / 1卷 / 05期

基金：

中国博士后科学基金; 中国国家自然科学基金;

关键词：

GRAPHENE OXIDE; CARBON; FLUORESCENCE; FILMS;

D O I：

10.1039/c2tb00055e

中图分类号：

TB3 [工程材料学]; R318.08 [生物材料学];

学科分类号：

0805 ; 080501 ; 080502 ;

摘要：

Chemically converted graphene (CCG) was found to effectively quench the fluorescence emission of Cy3 dye 1 (the intensity is down to 1/38 of 1 alone) in aqueous solution, due to the formation of a CCG-1 hybrid. After the addition of a certain amount of bovine serum albumin (BSA) into the above-mentioned system, about 60 times fluorescence enhancement was observed for the hybrid CCG-1. This was employed to discriminate BSA: the fluorescence intensity was found to be proportional to the BSA added in the concentration range from 0 to 8 x 10(-6) M, and the BSA detection limit was down to 5 x 10(-8) M.

引用

页码：693 / 697

页数：5

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