Evaluation of the Efficacy of Zactran® Injectable Solution (150 mg gamithromycin/ml) in the Control of Bovine Respiratory disease in Germany in Comparison to Draxxin® Injectable Solution (100 mg Tulathromycin/ml)

被引:0
作者
Fischer, F. [1 ]
Luellmann, S.
Boelle, L.
Lauseker, M. [2 ]
Ricken, G.
Forbes, A. B. [3 ]
机构
[1] Merial GmbH, Soldnermoos 6, D-85399 Hallbergmoos, Germany
[2] Ludwig Maximilians Univ Munchen, Inst Med Informat Verarbeitung Biometrie & Epidem, Munich, Germany
[3] Merial, F-69007 Lyon, France
来源
INTERNATIONAL JOURNAL OF APPLIED RESEARCH IN VETERINARY MEDICINE | 2013年 / 11卷 / 01期
关键词
bovine respiratory disease; gamithromycin; tulathromycin;
D O I
暂无
中图分类号
S85 [动物医学(兽医学)];
学科分类号
0906 ;
摘要
A field trial was conducted to evaluate the efficacy of Zactran injectable solution ( 150 mg gamithromycin/ml) in the control of bovine respiratory disease in comparison to Draxxin injectable solution ( 100 mg tulathromycin/ml) on a German commercial calf rearing/fattening farm. One hundred and twenty newly arrived Brown Swiss male calves judged to be at high risk of developing bovine respiratory disease were split into two equal groups. The animals in each group were treated either with gamithromycin at 6 mg/kg or with tulathromycin at 2.5 mg/kg by subcutaneous injection. All animals were weighed individually on Days 1, 69, and 100. Weight gain was defined as the main criterion for comparison in this study. Animals treated with Zactran had numerically higher weight gains throughout the study, although differences between those treated with Zactran and Draxxin were not statistically significant.
引用
收藏
页码:70 / 76
页数:7
相关论文
共 18 条
[1]   FACTORS AFFECTING INCIDENCE OF PNEUMONIA IN GROWING BULLS [J].
ANDREWS, AH .
VETERINARY RECORD, 1976, 98 (08) :146-149
[2]   The role of Mycoplasma bovis in bovine respiratory disease outbreaks in veal calf feedlots [J].
Arcangioli, Marie-Anne ;
Duet, Arnaud ;
Meyer, Gilles ;
Dernburg, Ann ;
Bezille, Pierre ;
Poumarat, Francois ;
Le Grand, Dominique .
VETERINARY JOURNAL, 2008, 177 (01) :89-93
[3]   Temporal distributions of respiratory disease events within cohorts of feedlot cattle and associations with cattle health and performance indices [J].
Babcock, A. H. ;
Renter, D. G. ;
White, B. J. ;
Dubnicka, S. R. ;
Scott, H. M. .
PREVENTIVE VETERINARY MEDICINE, 2010, 97 (3-4) :198-219
[4]   LESIONS IN THE CARCASSES AND VISCERA OF VERY YOUNG SLAUGHTER CALVES CONDEMNED AT POSTMORTEM MEAT INSPECTION [J].
BISS, ME ;
ALLEY, MR ;
MADIE, P ;
HATHAWAY, SC .
NEW ZEALAND VETERINARY JOURNAL, 1994, 42 (04) :121-127
[5]   The medicine and epidemiology of bovine respiratory disease in feedlots [J].
Cusack, PMV ;
McMeniman, N ;
Lean, IJ .
AUSTRALIAN VETERINARY JOURNAL, 2003, 81 (08) :480-487
[6]   Board-invited review: Recent advances in management of highly stressed, newly received feedlot cattle [J].
Duff, G. C. ;
Galyean, M. L. .
JOURNAL OF ANIMAL SCIENCE, 2007, 85 (03) :823-840
[7]   Determination of the Duration of Antibacterial Efficacy following Administration of Gamithromycin Using a Bovine Mannheimia haemolytica Challenge Model [J].
Forbes, A. B. ;
Ramage, C. ;
Sales, J. ;
Baggott, D. ;
Donachie, W. .
ANTIMICROBIAL AGENTS AND CHEMOTHERAPY, 2011, 55 (02) :831-835
[8]  
Giguère S, 2011, INT J APPL RES VET M, V9, P342
[9]   Bacterial Pathogens of the Bovine Respiratory Disease Complex [J].
Griffin, Dee ;
Chengappa, M. M. ;
Kuszak, Jennifer ;
McVey, D. Scott .
VETERINARY CLINICS OF NORTH AMERICA-FOOD ANIMAL PRACTICE, 2010, 26 (02) :381-+
[10]   Pharmacokinetics of gamithromycin in cattle with comparison of plasma and lung tissue concentrations and plasma antibacterial activity [J].
Huang, R. A. ;
Letendre, L. T. ;
Banav, N. ;
Fischer, J. ;
Somerville, B. .
JOURNAL OF VETERINARY PHARMACOLOGY AND THERAPEUTICS, 2010, 33 (03) :227-237