A decade of the modified Atkins diet (2003-2013): Results, insights, and future directions

被引：81
作者：
Kossoff, Eric H. [1 ]
Cervenka, Mackenzie C. [1 ]
Henry, Bobbie J. [1 ]
Haney, Courtney A. [1 ]
Turner, Zahava [1 ]
机构：
[1] Johns Hopkins Univ, Sch Med, Baltimore, MD USA
来源：
EPILEPSY & BEHAVIOR | 2013年 / 29卷 / 03期
关键词：
Atkins; Ketosis; Ketogenic; Diet; Epilepsy; INTRACTABLE CHILDHOOD EPILEPSY; RANDOMIZED CONTROLLED-TRIAL; TYPE-1 DEFICIENCY SYNDROME; KETOGENIC DIET; EFFICACY; THERAPY; ADULTS; CHILDREN; SEIZURES; TOLERABILITY;
D O I：
10.1016/j.yebeh.2013.09.032
中图分类号：
B84 [心理学]; C [社会科学总论]; Q98 [人类学];
学科分类号：
03 ; 0303 ; 030303 ; 04 ; 0402 ;
摘要：
The modified Atkins diet has been used since 2003 for the treatment of children and adults with refractory epilepsy. This "alternative" ketogenic diet is started in clinic, without fasting, hospitalization, and restriction of protein, calories, or fluid intake. Now after 10years of continued use, approximately 400 patients have been reported in over 30 studies of the modified Atkins diet as treatment for intractable seizures, with results demonstrating similar efficacy to the ketogenic diet and improved tolerability. The modified Atkins diet is being increasingly used in the adult population. Clinical trials have provided insight into the mechanisms of action of dietary therapies overall. This review will discuss the past decade of experience with the modified Atkins diet as well as predictions for its role in the treatment of epilepsy a decade from now. (C) 2013 Elsevier Inc. All rights reserved.
引用
收藏
页码：437 / 442
页数：6
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