Two New Compounds Isolated from Liriope muscari

被引:7
作者
Li, Wen-Jie [1 ]
Zhang, Zhi-Hao [1 ,2 ]
Cheng, Xian-Long [1 ]
Liu, Jing [1 ]
He, Yi [1 ]
Zhou, Chao [1 ,3 ]
Guo, Ying [1 ]
Lin, Rui-Chao [1 ,2 ]
Wang, Gang-Li [1 ]
机构
[1] Natl Inst Food & Drug Control, Beijing 100050, Peoples R China
[2] Macau Univ Sci & Technol, Fac Chinese Med, Macao, Peoples R China
[3] QiQiHaEr Inst Food & Drug Control, Qiqihar 161000, Peoples R China
关键词
liliaceae; Liriope muscari; norcurlignan; limlactone; antioxidant activity; EUDESMANE SESQUITERPENE GLYCOSIDES; PHENOLIC-COMPOUNDS; CONSTITUENTS; PROLIFERA; LIGNANS;
D O I
10.3390/molecules17088773
中图分类号
Q5 [生物化学]; Q7 [分子生物学];
学科分类号
071010 ; 081704 ;
摘要
Two new compounds, (2S, 3R)-methyl 7-hydroxy-2-(4-hydroxy-3-methoxyphenyl)-3-(hydroxymethyl)-2,3-dihydrobenzofuran-5-carboxylate (1) and (4R, 5S)-5-(3-hydroxy-2,6-dimethylphenyl)-4-isopropyldihydrofuran-2-one (2), tentatively named norcurlignan and limlactone, respectively, were isolated from Liriope muscari, together with the known compound (-)-pinoresinol (3). The structures of these compounds were elucidated and characterized on the basis of 1D NMR, 2D NMR, CD and MS data. The in vitro antioxidant activities of compounds 1-3 were assessed by the DPPH and ABTS scavenging methods.
引用
收藏
页码:8773 / 8781
页数:9
相关论文
共 18 条
[1]  
Beecham A.F., 1968, TETRAHEDRON LETT, V9, P3591
[2]   Norneolignan and phenols from Curculigo capitulata [J].
Chang, WL ;
Lee, SS .
PHYTOCHEMISTRY, 1998, 49 (07) :2133-2136
[3]  
Cheng Z.H., 2005, ZHONG CAO YAO, V36, P823
[4]  
Cheng ZH, 2006, CHINESE CHEM LETT, V17, P31
[5]   cis-Eudesmane sesquiterpene glycosides from Liriope muscari and Ophiopogon japonicus [J].
Cheng, ZH ;
Wu, T ;
Bligh, SWA ;
Bashall, A ;
Yu, BY .
JOURNAL OF NATURAL PRODUCTS, 2004, 67 (10) :1761-1763
[6]   DICHOTOMOUS REGIOCHEMISTRY OF ALDEHYDE AND KETONE IN THE REACTION WITH DITHIO-SUBSTITUTED CROTYLLITHIUM [J].
FANG, JM ;
HONG, BC ;
LIAO, LF .
JOURNAL OF ORGANIC CHEMISTRY, 1987, 52 (05) :855-861
[7]   Two new benzofuran derivatives with anti-inflammatory activity from Liriope spicata var. prolifera [J].
Hu, Zheng-Fang ;
Chen, Lin-Lin ;
Qi, Jin ;
Wang, Yan-Hui ;
Zhang, Hong ;
Yu, Bo-Yang .
FITOTERAPIA, 2011, 82 (02) :190-192
[8]   A new eudesmane sesquiterpene glycosides from Liriope muscari [J].
Jiang, Chang ;
Liu, Zhi-Hua ;
Li, Li ;
Lin, Bin-Bin ;
Yang, Fan ;
Qin, Min-Jian .
JOURNAL OF ASIAN NATURAL PRODUCTS RESEARCH, 2012, 14 (05) :491-495
[9]   Phenolic Compounds and Antioxidant Activities of Liriope muscari [J].
Li, Wen Jie ;
Cheng, Xian Long ;
Liu, Jing ;
Lin, Rui Chao ;
Wang, Gang Li ;
Du, Shu Shan ;
Liu, Zhi Long .
MOLECULES, 2012, 17 (02) :1797-1808
[10]   LIGNANS AND OTHER CONSTITUENTS FROM SOUTH AND CENTRAL AMERICAN ZANTHOXYLUM SPECIES [J].
MARCOS, M ;
JIMENEZ, C ;
VILLAVERDE, MC ;
RIGUERA, R ;
CASTEDO, L ;
STERMITZ, F .
PLANTA MEDICA, 1990, 56 (01) :89-91