Surrogate markers of disease in mastocytosis

被引：43

作者：

Akin, C ^{[1
]}

Metcalfe, DD ^{[1
]}

机构：

[1] NIAID, Lab Allerg Dis, NIH, Bethesda, MD 20892 USA

来源：

INTERNATIONAL ARCHIVES OF ALLERGY AND IMMUNOLOGY | 2002年 / 127卷 / 02期

关键词：

mastocytosis; urticaria pigmentosa; surrogate markers; tryptase; mast cells;

D O I：

10.1159/000048184

中图分类号：

R392 [医学免疫学];

学科分类号：

100102 ;

摘要：

Measurement of surrogate mast cell-related products in blood or urine is often performed to assess disease extent in evaluating patients with mastocytosis. Serum tryptase and 24-hour urine histamine metabolites are the most commonly used surrogate markers of mastocytosis. In addition, several novel markers including soluble CD117 and soluble CD25 have been identified in recent studies. The utility and the pitfalls of each of these measurements are discussed. Copyright (C) 2002 S. Karger AG, Basel.

引用

页码：133 / 136

页数：4