Characterization of Andean Blueberry in Bioactive Compounds, Evaluation of Biological Properties, and In Vitro Bioaccessibility

被引：21

作者：

Baenas, Nieves ^{[1
]}

Ruales, Jenny ^{[2
]}

Moreno, Diego A. ^{[3
]}

Barrio, Daniel Alejandro ^{[4
]}

Stinco, Carla M. ^{[5
]}

Martinez-Cifuentes, Gabriela ^{[2
]}

Melendez-Martinez, Antonio J. ^{[5
]}

Garcia-Ruiz, Almudena ^{[2
,6
]}

机构：

[1] Univ Murcia, Reg Campus Int Excellence Campus Mare Nostrum, Fac Vet Sci, Dept Food Technol Food Sci & Nutr, Murcia 30100, Spain

[2] Escuela Politecn Natl, Dept Food Sci & Biotechnol, Quito 17012759, Ecuador

[3] CSIC, CEBAS, Dept Food Sci & Technol, Phytochem & Hlth Foods Lab, Campus Espinardo,Edificio 25, E-30100 Murcia, Spain

[4] Univ Nacl Rio Negro, CIT Rio Negro, Don Bosco Leloir S-N, RA-8500 Viedma, Argentina

[5] Univ Seville, Dept Nutr & Food Sci, Food Colour & Qual Lab, Fac Farm, Seville 41012, Spain

[6] UAM, Madrid Inst Adv Studies IMDEA Food, Lab Epigenet Lipid Metab, CEI,CSIC, Madrid 28049, Spain

来源：

FOODS | 2020年 / 9卷 / 10期

关键词：

mortino; Vaccinium floribundum; HPLC-MS/MS; anthocyanins; antioxidant; antimicrobial; toxicity; zebrafish; VACCINIUM-FLORIBUNDUM KUNTH; ANTIOXIDANT CAPACITY; PHENOLIC-COMPOUNDS; FRUITS; IDENTIFICATION; ANTHOCYANINS; POLYPHENOLS; BLACKBERRY; BERRIES; VALIDATION;

D O I：

10.3390/foods9101483

中图分类号：

TS2 [食品工业];

学科分类号：

0832 ;

摘要：

The aim of this study was to evaluate Andean blueberries (Vaccinium floribundum Kunth) from Ecuador as a potential functional ingredient for the food and pharmaceutical industries. The analysis of bioactive compounds by HPLC-DAD-MSn determined a high content of (poly)phenols, mainly anthocyanins, and the presence of the carotenoid lutein. Regarding its biological properties, Andean blueberry did not show toxicity by the zebrafish embryogenesis test, showing also a lack of the antinutrients lectins. Moreover, the results of in vitro and in vivo antioxidant capacity evaluation suggested its possibility to be used as natural antioxidant. This fruit also exhibited antimicrobial activity toward Staphylococcus aureus and Escherichia coli in low doses. Finally, in vitro gastrointestinal (GI) digestion showed a partial bioaccessibility of (poly) phenols (similar to 50% at the final step), showing high antioxidant capacity in the different GI phases. These results revealed Andean blueberry as an interesting candidate for being used as a functional ingredient and the development of further in vivo and clinical assays.

引用

页数：16

共 56 条

[1] LC-MSn identification and characterization of the phenolic compounds from the fruits of Flacourtia indica (Burm. F.) Merr. and Flacourtia inermis Roxb. [J].