Implications of the changing epidemiology of inflammatory bowel disease in a changing world

被引:119
作者
Agrawal, Manasi [1 ,2 ]
Jess, Tine [1 ,3 ]
机构
[1] Aalborg Univ, Ctr Mol Predict Inflammatory Bowel Dis PREDICT, Dept Clin Med, Copenhagen, Denmark
[2] Icahn Sch Med Mt Sinai, Dr Henry D Janowitz Div Gastroenterol, 1 Gustave L Levy Pl, New York, NY 10029 USA
[3] Aalborg Univ Hosp, Dept Gastroenterol & Hepatol, Aalborg, Denmark
关键词
Crohn's disease; epidemiology; inflammatory bowel disease; prevention; ulcerative colitis; POPULATION-BASED COHORT; CROHNS-DISEASE; RISK; COLITIS; ASSOCIATION; CHILDHOOD; EXPOSURE; IBD;
D O I
10.1002/ueg2.12317
中图分类号
R57 [消化系及腹部疾病];
学科分类号
摘要
The epidemiology of inflammatory bowel disease (IBD) has undergone considerable shifts since its emergence in the Western world over a century ago, especially in the last few decades, with increasing global burden of disease. IBD incidence continues to rise in developed countries in all age groups which is contributing to compounding prevalence. Further, IBD incidence is rising sharply in Asia and other recently developed and developing countries. In this review, we discuss the implications of changing trends of IBD epidemiology. First, changing patterns provide insights into IBD causes, as they occur concurrent with shifts in the environment, cultures, and attitudes. Understanding the impact of the environment on IBD risk can help towards prediction and prevention strategies. Second, we must prepare healthcare systems for the rising burden of IBD and address it at various levels towards improving outcomes and health, overall.
引用
收藏
页码:1113 / 1120
页数:8
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