Role of the lamina cribrosa in the pathogenesis of glaucoma. A review of the literature

被引:0
作者
Bastelica, P. [1 ]
Labbe, A. [1 ,2 ,3 ,4 ]
El Maftouhi, A. [1 ,5 ]
Hamard, P. [1 ]
Paques, M. [2 ,4 ,6 ]
Baudouin, C. [1 ,2 ,3 ,4 ]
机构
[1] IHU FOReSIGHT, Ctr Hosp Natl Ophtalmol Quinze Vingts, Serv 3, 28 Rue Charenton, F-75012 Paris, France
[2] Sorbonne Univ, Inst Vis, IHU FOReSIGHT, 17 Rue Moreau, F-75012 Paris, France
[3] HP Univ Versailles St Quentin Yvelines, Hop Ambroise Pare, AP HP, 9 Ave Charles Gaulle, F-92100 Boulogne Billancourt, France
[4] IHU FOReSIGHT, Ctr Hosp Natl Ophtalmol Quinze Vingts, Ctr Invest Clin 1423, Direct Hospitalisat & Soins,INSERM, 28 Rue Charenton, F-75012 Paris, France
[5] Ctr Ophtalmol Rabelais, 2 Rue Antoine St Exupery, F-69002 Lyon, France
[6] IHU FOReSIGHT, Ctr Hosp Natl Ophtalmol Quinze Vingts, Serv 4, 28 Rue Charenton, F-75012 Paris, France
来源
JOURNAL FRANCAIS D OPHTALMOLOGIE | 2022年 / 45卷 / 08期
关键词
Lamina cribrosa; Glaucoma; Intraocular pressure; Optic nerve; Optical coherence tomography; Adaptative optics; OPTIC-NERVE-HEAD; OPEN-ANGLE GLAUCOMA; INTRAOCULAR-PRESSURE ELEVATION; REGULATED GENE-TRANSCRIPTION; CEREBROSPINAL-FLUID PRESSURE; COHERENCE TOMOGRAPHY IMAGES; NORMAL-TENSION GLAUCOMA; AGE-RELATED-CHANGES; EXTRACELLULAR-MATRIX; HIGH-SPEED;
D O I
10.1016/j.jfo.2022.03.003
中图分类号
R77 [眼科学];
学科分类号
100212 ;
摘要
Located within the scleral canal, the lamina cribrosa is a sieve-like structure sepa-rating the intraocular and retrobulbar portions of the optic nerve. Identified as the main site of axonal damage in glaucomatous optic neuropathy, the study of the lamina cribrosa has been of great interest for many years. Numerous studies have explored the histological and morpho-logical characteristics of the laminar region in healthy subjects as well as glaucoma patients. More recently, the development of adaptive optics systems and new generations of OCT has allowed great progress in the understanding of the pathogenesis of glaucoma and has opened new perspectives for the improvement of diagnostic procedures.(c) 2022 Elsevier Masson SAS. All rights reserved.
引用
收藏
页码:952 / 966
页数:15
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