Synthesis of some novel (2-oxo-3-(arylimino) indolin-1-yl)-N-aryl acetamides and evaluation as antimicrobial agents

被引：3

作者：

Debnath, Biplab ^{[1
]}

Ganguly, Swastika ^{[1
]}

机构：

[1] Birla Inst Technol, Dept Pharmaceut Sci & Technol, Ranchi, Bihar, India

来源：

TOXICOLOGICAL AND ENVIRONMENTAL CHEMISTRY | 2015年 / 97卷 / 06期

关键词：

isatin derivatives; synthesis; antimicrobial activity; MIC; ISATIN; ANTIBACTERIAL; DERIVATIVES; ANTIFUNGAL; SCHIFF; BASES;

D O I：

10.1080/02772248.2015.1061524

中图分类号：

X [环境科学、安全科学];

学科分类号：

08 ; 0830 ;

摘要：

A series of sixteen 2-oxo-3-(arylimino) indolin-1-yl)-N-aryl acetamide derivatives were synthesized, characterized by physical and spectral data (IR, H-1 nuclear magnetic resonance (NMR), and mass spectrometry), and evaluated for their antibacterial and antifungal activities against various pathogenic microorganisms. Some of the synthesized compounds showed promising antibacterial and antifungal activities, the best being 2-(3-(4-chlorophenylimino)-2-oxoindolin-1-yl)-N-(3-methoxyphenyl) acetamide.

引用

页码：741 / 753

页数：13

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