False-positive Fentanyl Urine Detection after Initiation of Labetalol Treatment for Hypertension in Pregnancy: A Case Report

被引：3
作者：
Wanar, Amita [1 ]
Isley, Breanna Cassidy [2 ]
Saia, Kelley [1 ]
Field, Thomas A. [3 ]
机构：
[1] Boston Univ, Sch Med, Dept Obstet & Gynecol, Boston, MA USA
[2] Wake Forest Sch Med, Winston Salem, NC USA
[3] Oregon State Univ, Coll Educ, Corvallis, OR USA
来源：
JOURNAL OF ADDICTION MEDICINE | 2022年 / 16卷 / 06期
关键词：
fentanyl; labetalol; hypertension; false positive; pregnancy; CARE;
D O I：
10.1097/ADM.0000000000001010
中图分类号：
R194 [卫生标准、卫生检查、医药管理];
学科分类号：
摘要：
Background: Labetalol hydrochloride (LH) is a pharmacologic treatment for hypertensive disease (HD) in pregnancy. However, for pregnant persons with substance use disorders (SUDs), LH may interfere with urine drug testing. Case Summary: We present 3 pregnant or postpregnant persons with SUDs who experienced presumptive positive urine immunoassays for fentanyl while prescribed LH for perinatal HD. Discussion: Labetalol hydrochloride treatment for HD in pregnancy can result in presumptive positive urine immunoassays for fentanyl. Unrecognized or misinterpreted, this phenomenon can lead to significant consequences for pregnant and postpartum persons with co-occurring substance use and hypertensive disorders. Clinicians caring for pregnant persons with SUDs must be aware of this phenomenon and its sequelae when ordering and interpreting urine immunoassays for fentanyl.
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收藏
页码：E407 / E409
页数：3
相关论文
共 15 条
  • [1] Ailes Elizabeth C, 2015, MMWR Morb Mortal Wkly Rep, V64, P37
  • [2] [Anonymous], 1975, FENTANYL URINE HEIA
  • [3] [Anonymous], 2021, LABETALOL HYDROCHLOR
  • [4] Hypertension in Women of Reproductive Age in the United States: NHANES 1999-2008
    Bateman, Brian T.
    Shaw, Kate M.
    Kuklina, Elena V.
    Callaghan, William M.
    Seely, Ellen W.
    Hernandez-Diaz, Sonia
    [J]. PLOS ONE, 2012, 7 (04):
  • [5] Increase in Prescription Opioid Use During Pregnancy Among Medicaid-Enrolled Women
    Desai, Rishi J.
    Hernandez-, Sonia
    Bateman, Brian T.
    Huybrechts, Krista F.
    [J]. OBSTETRICS AND GYNECOLOGY, 2014, 123 (05) : 997 - 1002
  • [6] Increasing pregnancy-related use of prescribed opioid analgesics
    Epstein, Richard A.
    Bobo, William V.
    Martin, Peter R.
    Morrow, James A.
    Wang, Wei
    Chandrasekhar, Rameela
    Cooper, William O.
    [J]. ANNALS OF EPIDEMIOLOGY, 2013, 23 (08) : 498 - 503
  • [7] The CARE guidelines: consensus-based clinical case report guideline development
    Gagnier, Joel J.
    Kienle, Gunver
    Altman, Douglas G.
    Moher, David
    Sox, Harold
    Riley, David
    [J]. JOURNAL OF CLINICAL EPIDEMIOLOGY, 2014, 67 (01) : 46 - 51
  • [8] A LABETALOL METABOLITE WITH ANALYTICAL CHARACTERISTICS RESEMBLING AMPHETAMINES
    GILBERT, RB
    PENG, PI
    WONG, D
    [J]. JOURNAL OF ANALYTICAL TOXICOLOGY, 1995, 19 (02) : 84 - 86
  • [9] Appropriate Use of Drug Testing in Clinical Addiction Medicine
    Jarvis, Margaret
    Williams, Jessica
    Hurford, Matthew
    Lindsay, Dawn
    Lincoln, Piper
    Giles, Leila
    Luongo, Peter
    Safarian, Taleen
    [J]. JOURNAL OF ADDICTION MEDICINE, 2017, 11 (03) : 163 - 173
  • [10] Clinical care for opioid-using pregnant and postpartum women: the role of obstetric providers
    Jones, Hendree E.
    Deppen, Krisanna
    Hudak, Mark L.
    Leffert, Lisa
    McClelland, Carol
    Sahin, Leyla
    Starer, Jacquelyn
    Terplan, Mishka
    Thorp, John M., Jr.
    Walsh, James
    Creanga, Andreea A.
    [J]. AMERICAN JOURNAL OF OBSTETRICS AND GYNECOLOGY, 2014, 210 (04) : 302 - 310
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