Successful treatment of genital Bowen's disease with imiquimod 5% cream

被引：3

作者：

Kishi, Chikako ^{[1
]}

Shimizu, Akira ^{[1
]}

Kato, Madoka ^{[1
]}

Amano, Hiroo ^{[1
]}

Ishikawa, Osamu ^{[1
]}

机构：

[1] Gunma Univ, Grad Sch Med, Dept Dermatol, Maebashi, Gunma 3718511, Japan

来源：

INTERNATIONAL JOURNAL OF STD & AIDS | 2015年 / 26卷 / 10期

关键词：

Bowen's disease in the vulva; vulvar intraepithelial neoplasia; VIN; treatment; HPV; human papillomavirus; imiquimod; HUMAN-PAPILLOMAVIRUS; PRIMERS; DNA;

D O I：

10.1177/0956462414553615

中图分类号：

R392 [医学免疫学]; Q939.91 [免疫学];

学科分类号：

100102 ;

摘要：

A 64-year-old Japanese woman was diagnosed as having Bowen's disease on the vulva. The histopathological findings revealed papillomatosis, koilocytosis and clumping cells with atypical nuclei. Human papillomavirus DNA was not detected on polymerase chain reaction using consensus primers. The lesion was successfully treated with topical imiquimod 5% cream after two months. Histopathologically, no atypical cells were observed after treatment. Imiquimod can be a potential treatment modality for lesions that are difficult to treat with surgical excision.

引用

页码：752 / 754

页数：3

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