Polysaccharide from Seeds of Plantago asiatica L. Increases Short-Chain Fatty Acid Production and Fecal Moisture along with Lowering pH in Mouse Colon

被引：148

作者：

Hu, Jie-Lun ^{[1
]}

Nie, Shao-Ping ^{[1
]}

Min, Fang-Fang ^{[1
]}

Xie, Ming-Yong ^{[1
]}

机构：

[1] Nanchang Univ, State Key Lab Food Sci & Technol, Nanchang 330047, Peoples R China

来源：

JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY | 2012年 / 60卷 / 46期

基金：

中国国家自然科学基金;

关键词：

Plantago asiatica L; polysaccharide; short-chain fatty acids; colonic content moisture; colon pH; SOLID-PHASE MICROEXTRACTION; IN-VITRO FERMENTATION; DIETARY FIBER; LARGE-BOWEL; BILE-ACIDS; CANCER; OLIGOSACCHARIDES; MASS; CARBOHYDRATE; SURVIVAL;

D O I：

10.1021/jf302169u

中图分类号：

S [农业科学];

学科分类号：

09 ;

摘要：

Mice (20.0 +/- 2.0 g, n = 48 per group) were given 30 days oral administration of polysaccharide-from Plantago asiatica L. seeds at the dose of 04 g/kg body weight by gavage to investigate the effects of the polysaccharide on mouse colon. Results showed that the concentrations of total short-chain fatty acids (SCFA), acetic, propionic, and n-butyric acids in mouse colonic content of polysaccharide treated group were all significantly higher than that of control group (water) (p < 0.05). In addition, moisture of mouse colonic content of polysaccharide treated group was also notably higher than that of the control group (p < 0.05) indicating the intake of polysaccharide from P. asiatica L. resulted in a stronger water-holding capacity for colonic content throughout the experimental period. Furthermore, a decreased pH (from 7.5 +/- 0.1 to 7.2 +/- 0.1) was observed in mouse colon of the polysaccharide treated group compared with the control group (pH from 7.5 +/- 0.1 to 7.5 +/- 0.1). These results suggested that the intake of the polysaccharide from P. asiatica L. might be beneficial for the colon health.

引用

页码：11525 / 11532

页数：8

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