Zygomycosis over-infection during voriconazole therapy for aspergillosis in a heart transplant patient, successfully treated with liposomal amphotericin and posaconazole

被引：5

作者：

Bourke, P. ^{[1
]}

Castro, P. ^{[1
]}

Rabagliati, R. ^{[2
]}

Beltran, C. ^{[3
]}

Verdejo, H. ^{[1
]}

Winter, J. L. ^{[1
]}

Bourge, R. C. ^{[4
]}

机构：

[1] Pontificia Univ Catolica Chile, Fac Med, Escuela Med, Div Enfermedades Cardiovasc, Santiago, Chile

[2] Pontificia Univ Catolica Chile, Fac Med, Escuela Med, Dept Med Interna, Santiago, Chile

[3] Pontificia Univ Catolica Chile, Fac Med, Escuela Med, Dept Otorrinolaringol, Santiago, Chile

[4] Univ Alabama Birmingham, Dept Med, Div Cardiovasc Dis, Birmingham, AL 35294 USA

来源：

TRANSPLANT INFECTIOUS DISEASE | 2012年 / 14卷 / 05期

关键词：

zygomycosis; heart transplant; FUNGAL-INFECTIONS; RECIPIENTS; PREVENTION;

D O I：

10.1111/j.1399-3062.2012.00772.x

中图分类号：

R392 [医学免疫学]; Q939.91 [免疫学];

学科分类号：

100102 ;

摘要：

Aspergillosis and zygomycosis are life-threatening fungal infections in immunocompromised patients. We report a heart transplant recipient with an early pulmonary invasive aspergillosis successfully treated with association of voriconazole and caspofungin. Zygomycosis sinusitis, which was diagnosed while he still was on voriconazole therapy, was successfully treated with the use of combination antifungal therapy including liposomal amphotericin plus posaconazole and conservative surgical debridement.

引用

页码：E56 / E59

页数：4

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