An HBV-HIV Co-infected Patient Treated with Tenofovir-based Therapy who Achieved HBs Antigen/Antibody Seroconversion

被引：0

作者：

Watanabe, Takao ^{[1
]}

Tokumoto, Yoshio ^{[1
]}

Hirooka, Masashi ^{[1
]}

Koizumi, Yohei ^{[1
]}

Tada, Fujimasa ^{[1
]}

Ochi, Hironori ^{[1
]}

Abe, Masanori ^{[1
]}

Kumagi, Teru ^{[1
]}

Ikeda, Yoshio ^{[1
]}

Matsuura, Bunzo ^{[1
]}

Takada, Kiyonori ^{[2
]}

Hiasa, Yoichi ^{[1
]}

机构：

[1] Ehime Univ, Grad Sch Med, Dept Gastroenterol & Metabol, Matsuyama, Ehime 790, Japan

[2] Ehime Univ, Grad Sch Med, Postgrad Clin Training Ctr, Matsuyama, Ehime 790, Japan

来源：

INTERNAL MEDICINE | 2014年 / 53卷 / 12期

关键词：

hepatitis B virus; human immunodeficiency virus; co-infection; tenofovir; seroconversion; HEPATITIS-B-VIRUS; HUMAN-IMMUNODEFICIENCY-VIRUS; POLYMERASE MUTATIONS; COINFECTED PATIENTS; VIRAL-HEPATITIS; LAMIVUDINE; JAPAN; SUSCEPTIBILITY; EPIDEMIOLOGY; INDIVIDUALS;

D O I：

10.2169/internalmedicine.53.2131

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

The present report describes a case of a patient with hepatitis B virus (HBV)-human immunodeficiency virus (HIV) co-infection who was treated with tenofovir disoproxil (TDF)-based highly active antiretroviral therapy (HAART) and who achieved HBs antigen (Ag)/antibody (Ab) seroconversion. An 18-year-old Japanese man with HIV and HBV co-infection presented to our hospital. His CD4 count was decreased, and TDF-based HARRT was started. At 30 months after initiation of therapy, HBsAg was not detected. At 36 months after initiation of therapy, HBsAb was detected. We conclude that TDF-based therapy is useful for the management of patients with HBV and HIV co-infection.

引用

页码：1343 / 1346

页数：4

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