Parkinson's disease: From bench to bedside

被引：46
作者：
Draoui, A. [1 ]
El Hiba, O. [1 ,2 ]
Aimrane, A. [1 ]
El Khiat, A. [1 ]
Gamrani, H. [1 ]
机构：
[1] Cadi Ayyad Univ, Fac Sci Semlalia, Neurosci Pharmacol & Environm Unit, Ave My Abdellah,BP 2390, Marrakech, Morocco
[2] Chouaib Doukkali Univ El Jadida, Fac Sci, Lab Biotechnol Biochem & Nutr, Route Ben Maachou,Ave Fac, El Jadida, Morocco
来源：
REVUE NEUROLOGIQUE | 2020年 / 176卷 / 7-8期
关键词：
Parkinson's disease; Symptomatology; Epidemiology; Pathophysiology; Etiology; Neuroinflammation; Risk factors; Treatments; NONMOTOR SYMPTOMS; DOPAMINERGIC MODULATION; ALPHA-SYNUCLEIN; GAMMA-KNIFE; WEIGHT-LOSS; PRODROMAL SYMPTOMS; ANIMAL-MODELS; DIAGNOSIS; MEMORY; PATHOPHYSIOLOGY;
D O I：
10.1016/j.neurol.2019.11.002
中图分类号：
R74 [神经病学与精神病学];
学科分类号：
摘要：
Parkinson's disease is a very complex public health problem with different etiologies and a wide range of clinical features including motor and non-motor symptoms. The aim of the current report is to review the latest advances in the understanding of PD etiologies, diagnosis, epidemiology and an overview of the earlier and latest advances in the management of PD, from L-DOPA to adult astroglia reprogramming into dopaminergic neurons in vivo. (C) 2019 Elsevier Masson SAS. All rights reserved.
引用
收藏
页码：543 / 559
页数：17
相关论文
共 122 条
[1]  
[Anonymous], PARKINSONISM RELA S1
[2]  
[Anonymous], 2014, RES POLITICS, DOI DOI 10.1101/CSHPERSPECT.A009357
[3]  
[Anonymous], CSH PERSPECT MED
[4]  
[Anonymous], 1817, An Essay on the Shaking Palsy
[5]  
ANOUTI A, 1995, WESTERN J MED, V162, P510
[6]   A reassessment of risks and benefits of dopamine agonists in Parkinson's disease [J].
Antonini, Angelo ;
Tolosa, Eduardo ;
Mizuno, Yoshikuni ;
Yamamoto, Mitsutoshi ;
Poewe, Werner H. .
LANCET NEUROLOGY, 2009, 8 (10) :929-937
[7]   Visual symptoms in Parkinson's disease and Parkinson's disease dementia [J].
Archibald, Neil K. ;
Clarke, Mike P. ;
Mosimann, Urs P. ;
Burn, David J. .
MOVEMENT DISORDERS, 2011, 26 (13) :2387-2395
[8]   The epidemiology of Parkinson's disease: risk factors and prevention [J].
Ascherio, Alberto ;
Schwarzschild, Michael A. .
LANCET NEUROLOGY, 2016, 15 (12) :1255-1270
[9]  
Benazzouz A, 2018, J NEUROL NEUROSURG P, V89, P572, DOI [10.1136/jnnp-2017-316241., DOI 10.1136/JNNP-2017-316241]
[10]   MDS research criteria for prodromal Parkinson's disease [J].
Berg, Daniela ;
Postuma, Ronald B. ;
Adler, Charles H. ;
Bloem, Bastiaan R. ;
Chan, Piu ;
Dubois, Bruno ;
Gasser, Thomas ;
Goetz, Christopher G. ;
Halliday, Glenda ;
Joseph, Lawrence ;
Lang, Anthony E. ;
Liepelt-Scarfone, Inga ;
Litvan, Irene ;
Marek, Kenneth ;
Obeso, Jose ;
Oertel, Wolfgang ;
Olanow, C. Warren ;
Poewe, Werner ;
Stern, Matthew ;
Deuschl, Guenther .
MOVEMENT DISORDERS, 2015, 30 (12) :1600-1609
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