ADAMTS13: what it does, how it works, and why it's important

被引：6
作者：
George, James N. [1 ]
机构：
[1] Univ Oklahoma, Hlth Sci Ctr, Coll Med, Dept Biostat & Epidemiol,Dept Med,Coll Publ Hlth, Oklahoma City, OK 73190 USA
来源：
TRANSFUSION | 2009年 / 49卷 / 02期
关键词：
THROMBOTIC THROMBOCYTOPENIC PURPURA; FACTOR-CLEAVING PROTEASE; FACTOR MULTIMERS; ANTIBODIES; GLYCOPROTEINS; SURFACE; VWF;
D O I：
10.1111/j.1537-2995.2008.02060.x
中图分类号：
R5 [内科学];
学科分类号：
1002 ; 100201 ;
摘要：
引用
收藏
页码：196 / 198
页数：3
相关论文
共 25 条
[1]   THROMBOTIC THROMBOCYTOPENIC PURPURA - REPORT OF 16 CASES AND REVIEW OF LITERATURE [J].
AMOROSI, EL ;
ULTMANN, JE .
MEDICINE, 1966, 45 (02) :139-+
[2]   Formation of platelet strings and microthrombi in the presence of ADAMTS-13 inhibitor does not require P-selectin or β3 integrin [J].
Chauhan, A. K. ;
Goerge, T. ;
Schneider, S. W. ;
Wagner, D. D. .
JOURNAL OF THROMBOSIS AND HAEMOSTASIS, 2007, 5 (03) :583-589
[3]   Systemic antithrombotic effects of ADAMTS13 [J].
Chauhan, AK ;
Motto, DG ;
Lamb, CB ;
Bergmeier, W ;
Dockal, M ;
Plaimauer, B ;
Scheiflinger, F ;
Ginsburg, D ;
Wagner, DD .
JOURNAL OF EXPERIMENTAL MEDICINE, 2006, 203 (03) :767-776
[4]   The combined roles of ADAMTS13 and VWF in murine models of TTP, endotoxemia, and thrombosis [J].
Chauhan, Anil K. ;
Walsh, Meghan T. ;
Zhu, Guojing ;
Ginsburg, David ;
Wagner, Denisa D. ;
Motto, David G. .
BLOOD, 2008, 111 (07) :3452-3457
[5]   ADAMTS13 binds to CD36: a potential mechanism for platelet and endothelial localization of ADAMTS13 [J].
Davis, Amanda K. ;
Makar, Robert S. ;
Stowell, Christopher P. ;
Kuter, David J. ;
Dzik, Walter H. .
TRANSFUSION, 2009, 49 (02) :206-213
[6]   ADAMTS-13 rapidly cleaves newly secreted ultralarge von Willebrand factor multimers on the endothelial surface under flowing conditions [J].
Dong, JF ;
Moake, JL ;
Nolasco, L ;
Bernardo, A ;
Arceneaux, W ;
Shrimpton, CN ;
Schade, AJ ;
McIntire, LV ;
Fujikawa, K ;
López, JA .
BLOOD, 2002, 100 (12) :4033-4039
[7]   Von Willebrand factor-cleaving protease in thrombotic thrombocytopenic purpura and the hemolytic-uremic syndrome [J].
Furlan, M ;
Robles, R ;
Galbusera, M ;
Remuzzi, G ;
Kyrle, PA ;
Brenner, B ;
Krause, M ;
Scharrer, I ;
Aumann, V ;
Mittler, U ;
Solenthaler, M ;
Lämmle, B .
NEW ENGLAND JOURNAL OF MEDICINE, 1998, 339 (22) :1578-1584
[8]   Extensive contacts between ADAMTS13 exosites and von Willebrand factor domain A2 contribute to substrate specificity [J].
Gao, Weiqiang ;
Anderson, Patricia J. ;
Sadler, J. Evan .
BLOOD, 2008, 112 (05) :1713-1719
[9]   Lessons learned from the Oklahoma thrombotic thrombocytopenic purpura-hemolytic uremic syndrome registry [J].
George, James N. ;
Terrell, Deirdra R. ;
Swisher, Karen K. ;
Vesely, Sara K. .
JOURNAL OF CLINICAL APHERESIS, 2008, 23 (04) :129-137
[10]  
Johnson KK, 2006, BLOOD, V108, p31A
123