Study on interaction of caffeine and theophylline with bovine serum albumins

被引：0

作者：

Bian, W ^{[1
]}

Wei, YL

Wang, YP

Dong, C

机构：

[1] Med Univ Shanxi, Taiyuan 030001, Peoples R China

[2] Shanxi Univ, Chem & Chem Engn Coll, Taiyuan 030006, Peoples R China

来源：

SPECTROSCOPY AND SPECTRAL ANALYSIS | 2006年 / 26卷 / 03期

关键词：

caffeine; theophylline; bovine serum albumin; fluorescence spectroscopy;

D O I：

暂无

中图分类号：

O433 [光谱学];

学科分类号：

0703 ; 070302 ;

摘要：

The interation of caffeine and theophylline with bovine serum albumins has been studied by fluorescence spectroscopy. The results indicated that enoxacin could bind with BSA strongly at molar ratio 1 : 1 and the equilibrium constants were K-c = 1.673 X 10(4) L circle mol(-1) and K-t = 6.802 X 10(3) L circle mol(-1), respectively. Good linear Stern-Volmer lines were observed on the fluorescence of BSA quenched by enoxacin of different concentration, indicating that the combination reaction of enoxacin with BSA is a single static quenching process.

引用

页码：505 / 508

页数：4