Silver Enhancement of Gold Nanoparticles for Biosensing: From Qualitative to Quantitative

被引:61
作者
Liu, Rui [1 ]
Zhang, Yue [1 ]
Zhang, Shuyue [1 ]
Qiu, Wei [1 ]
Gao, Ying [2 ]
机构
[1] Chengdu Univ Technol, Mineral Resources Chem Key Lab, Sichuan Higher Educ Inst, Coll Mat & Chem & Chem Engn, Chengdu 610059, Sichuan, Peoples R China
[2] Chengdu Univ Technol, Coll Nucl Technol & Automat Engn, Sichuan Prov Key Lab Nucl Technol Geol, Chengdu 610059, Sichuan, Peoples R China
基金
中国国家自然科学基金;
关键词
Silver enhancement; gold nanoparticles; biosensing; ICP-MS; amplification; PLASMA-MASS SPECTROMETRY; HUMAN-IMMUNODEFICIENCY-VIRUS; COLLOIDAL GOLD; SIGNAL AMPLIFICATION; ELECTRICAL DETECTION; COLORIMETRIC DETECTION; SCANOMETRIC DETECTION; IMMUNOSORBENT-ASSAY; AU NANOPARTICLES; NANOGOLD PROBE;
D O I
10.1080/05704928.2013.807817
中图分类号
TH7 [仪器、仪表];
学科分类号
0804 ; 080401 ; 081102 ;
摘要
The establishment and rapid progress in sensitive biosensing using immunogold silver enhancement has occurred in the past 30years. Its high sensitivity and simplicity have made immunogold silver enhancement a revolutionary technique for signal amplification in biosensing. This review focuses on the major applications of immunogold silver enhancement, with special emphasis on quantitative biosensing. In this review, the combinations of immunogold silver enhancement with a series of quantitative techniques, such as colorimetry, electrical and electrochemical methods, gravimetry, chemiluminescence, Raman spectroscopy, and inductively coupled plasma-mass spectrometry (ICP-MS), are discussed in detail. Immunogold silver enhancement has become one of the most useful methods in highly sensitive quantitative bioanalysis. The recent development of ICP-MS detection shows great potential in combination with immunogold silver enhancement.
引用
收藏
页码:121 / 138
页数:18
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